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Human skin can make serotonin and melatonin, which help protect and maintain it.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Changing how mesenchymal stromal cells are grown can improve their healing abilities.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

Stem cell niches are crucial for regulating stem cell renewal and differentiation, and understanding them can help in developing regenerative therapies.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.

Recombinant cytokine therapy can cause skin reactions ranging from mild to severe.

Low-oxygen conditions and ECM degradation products increase the healing abilities of perivascular stem cells.

The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

MDP hydrogel heals wounds faster and better than other treatments in diabetic mice.

The document concludes that rapid identification, isolation, and strict infection control are crucial to manage SARS outbreaks.

Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.

Exosomes from dermal papilla cells help hair growth by making hair follicle stem cells multiply and change.

Advanced human skin models improve drug development and could replace animal testing.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.