4 citations
,
January 2013 in “Genetics and Molecular Research” This study found that VEGF expression and microvessel density in hair follicles of Liaoning cashmere goats follow a bimodal pattern correlated with hair development throughout the year.
43 citations
,
April 2021 in “Angiogenesis” This review examines the evolving understanding of lymphatic vessel development, emphasizing new cellular mechanisms and lineage diversity, while discussing experimental methods and identifying key knowledge gaps.
100 citations
,
August 2008 in “American Journal Of Pathology” This study found that epidermal VEGF is crucial for maintaining skin barrier function in mice and may help explain psoriasis development following skin trauma due to its effects on angiogenesis and hyperplasia.
1 citations
,
April 2018 in “Journal of Investigative Dermatology” This study found that FZD2 is crucial for hair follicle formation and postnatal growth in mice and has a novel role in regulating early epidermal development, including stratification and cornification.
162 citations
,
July 2011 in “Biomacromolecules” This study found that chitosan nanofibrillar scaffolds accelerated skin wound healing in mice by enhancing cell adhesion, proliferation, and regeneration of epidermis and dermis compared to other forms.
90 citations
,
October 1996 in “Dermatologic Clinics” This study found that red ginseng oil may enhance hair growth and protect skin from UV damage in mouse models by promoting regenerative processes and reducing inflammation.
25 citations
,
February 2024 in “Biomaterials” In this study, iPSC-derived epidermal organoids demonstrated potential as a novel tool for regenerative medicine by producing high-performance extracellular vesicles that promote proliferation, migration, and angiogenesis in cell-free therapies for wound healing.
December 2025 in “Frontiers in Veterinary Science” In this study, researchers explored hair follicle development in Qianhua Mutton Merino sheep, identifying key genes like KRT27 and IGF-2 that impact this process, with findings suggesting significant molecular changes as sheep mature from newborn to one year old.
November 2025 in “ACS Omega” This study found that incorporating Canavalia ensiformis lectin into alginate and carboxymethylcellulose films enhanced angiogenic factor expression, suggesting these biopolymer films could be an effective alternative for wound treatment.
April 2025 in “Acta Dermato Venereologica” Topical minoxidil may cause cherry hemangiomas in some users.
2 citations
,
January 2009 This article reviews the development of a topical hair growth agent using natural extracts and reports no new clinical results, emphasizing the need for further evaluation of its efficacy.
136 citations
,
May 2019 in “Cells” This review discusses the advancements in intraoperative stem cell therapies and highlights their potential to improve hair regrowth, but it reports no new clinical results.
April 2018 in “Journal of Investigative Dermatology” This study found that a water-soluble peptide from chicken egg yolk, named Hair Growth Peptide, improved hair growth in mice and female pattern hair loss through increased IGF-1 and VEGF production.
In an animal study, researchers observed that simvastatin and Luteolin significantly increased hair growth and reduced hair loss in male mice, with improvements linked to their antioxidant and anti-inflammatory properties.
49 citations
,
November 2021 in “Annual review of pathology” This review discusses the regulatory roles of lysophospholipids like LPA and S1P in diseases such as fibrosis, neuropathic pain, and cancer, but reports no new clinical results.
3 citations
,
January 2022 in “Burns & Trauma” This study found that CTHRC1 is crucial for sweat gland function and vascular network integrity in mice, and its administration improved sweat gland performance by reconstructing nearby blood vessels.
71 citations
,
January 2020 in “Stem Cells International” This review discusses the biological features and clinical applications of epidermal stem cells in wound healing and tissue regeneration, emphasizing the need for further understanding of their mechanisms.
October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study constructed a comprehensive atlas of prenatal human skin, revealing that innate immune cells, such as macrophages, play a crucial role in skin morphogenesis by interacting with non-immune cells, influencing hair follicle formation and angiogenesis beyond their traditional immune functions.
November 2022 in “Journal of Investigative Dermatology” This study observed that three-dimensional cultures of dermal papilla cells enhanced endothelial cell migration and angiogenesis in vitro, which may improve vascularization in tissue-engineered skin constructs.
15 citations
,
June 2015 in “PLoS ONE” This study found that thymosin beta-4 overexpression in mice increased hair growth speed and density, likely by regulating P38/ERK/AKT signaling through VEGF expression.
14 citations
,
July 2021 in “Biomolecules” This study found that Centipeda minima extract promotes hair growth by activating Wnt/β-catenin, ERK, and JNK signaling pathways in human hair follicle dermal papilla cells.
11 citations
,
September 2012 in “Journal of Nanjing Medical University” In this study, cyclosporine A stimulated hair growth in mouse vibrissae organ culture by promoting matrix cell proliferation and altering growth factor expression.
10 citations
,
January 2013 in “Regenerative Medicine Research” This article discusses the potential for rejuvenating self-repair mechanisms to enhance regenerative medicine, but reports no new empirical findings.
5 citations
,
February 2016 in “Hanbang an i bi inhu pibugwa hakoeji/Hanbang an'i'bi'in'hu pibu'gwa haghoeji” This study found that HRHDT combined with microneedle therapy improved hair growth in a mouse model of alopecia more effectively than microneedle therapy alone.
3 citations
,
June 2017 in “Journal of Biomaterials Applications” This study demonstrated that keratin extract can stimulate hair growth by inducing the anagen phase in telogenic mice.
3 citations
,
October 2010 in “Placenta” This study found that the ALK5 inhibitor TP0427736 inhibited TGF-β signaling in cell and mouse models, suggesting potential as a new treatment for androgenic alopecia.
2 citations
,
August 2020 in “Natural Product Communications” This study found that the topical application of a mixture of Platycladus orientalis leaf extract and α-terpineol promoted hair growth in mice by inducing early anagen transition and increasing growth factor expressions.
1 citations
,
September 2018 in “Australasian Journal of Dermatology” In this report, a 2-year-old male with GAPO syndrome exhibited androgenetic-like alopecia with normal testosterone levels and telogen hair loss, which are novel findings for this condition.
January 2025 in “Yonsei Medical Journal” The study found that a novel mixture of mastic gum and peppermint extract increased hair growth and gloss in C57BL/6 mice, showing potential as a botanical alternative for promoting hair health.
January 2024 in “Journal of applied biological chemistry” This study found that Glehnia littoralis and Andrographis paniculata may support hair growth by protecting against oxidative stress and increasing VEGF and Wnt/β-catenin signaling in human hair follicle dermal papilla cells, with enhanced effects when combined.