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Acne can appear or persist in adulthood due to hormonal changes, external factors, or substance use, and requires appropriate treatment.

Diagnosing simple-virilizing congenital adrenal hyperplasia can be difficult and requires thorough testing and expert advice.

Mutations in the androgen receptor gene cause different levels of androgen insensitivity, making it hard to create simple tests for the condition.

Menopause and aging can affect women's quality of life and sexuality, but hormone therapies may help alleviate these issues.

Testosterone replacement can help women with low libido and mood, but they need to have enough estrogen first to avoid side effects.

Exposure to finasteride in the womb caused lasting reproductive issues in male rats.

Get head MRI for babies with achondroplasia early, use free immunoglobulin light chains to detect certain neurodevelopmental disorders, and video calls work for speech therapy in patients with facial anomalies.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Panax ginseng is generally safe with mild side effects and may have health benefits, but more research is needed.

Testosterone replacement may improve sexual desire and bone health in women with low androgen levels, but more research is needed on its long-term safety.

Excipients greatly affect how well curcumin nanocrystals penetrate the skin and target hair follicles.

With careful management, people with congenital adrenal hyperplasia can have successful pregnancies and become parents.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

Keratin genes change gradually during skin cell development and should be used carefully as biomarkers.

Hair loss in postmenopausal women due to ovarian hyperthecosis is rare, but removing the ovaries can significantly improve the condition.

Platelet Rich Plasma (PRP) shows promise for tissue repair and immune response, but more research is needed to fully understand it and optimize its use.

No single biomarker is reliable enough for diagnosing and assessing SLE.

17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.

Some common medications can harm male fertility, but many effects can be reversed.

An imbalance in gut bacteria is linked to skin immune diseases and may affect their outcomes and related health issues.

Testosterone replacement may help post-menopausal women with androgen insufficiency, but more research is needed on its benefits and risks.

Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.

Removing both ovaries may better treat increased male hormone levels and related symptoms in postmenopausal women when hormone therapy doesn't work.

Isotretinoin effectively treats severe acne and similar conditions, but has common, mostly reversible side effects, requiring careful patient monitoring.

Red ginseng may improve immunity, fatigue, memory, blood circulation, and menopausal symptoms, and is generally safe to consume.

Testosterone replacement may help postmenopausal women with sexual function and bone density, but suitable treatments are limited.

Zinc is important for skin health, and supplements can help treat various skin and hair disorders, but more research is needed for conditions like psoriasis and vitiligo.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Patients with Bohring-Opitz syndrome and ASXL1 mutations need regular kidney ultrasounds to check for tumors.

A 37-year-old male with severe skin and internal issues has a rare inherited skin condition called dystrophic epidermolysis bullosa.