21 citations
,
June 2018 in “Journal of Investigative Dermatology” Rats can't grow new hair follicles after skin wounds, unlike mice, due to differences in gene expression and response to WNT signaling.
5 citations
,
January 2020 in “Wiadomości lekarskie (Warsaw Poland)” Patients with both connective tissue disease and acid reflux are more likely to have certain symptoms and physical signs.
August 2022 in “Journal of Investigative Dermatology” A specific mutation in Kras causes abnormal tissue changes by making a cell signal continuously active, which disrupts normal cell coordination.
505 citations
,
December 2011 in “Journal of clinical oncology” MK-2206 was safe and effectively blocked AKT signaling in cancer patients, warranting more trials.
176 citations
,
April 2011 in “Science” Hair stem cell regeneration is controlled by signals that can explain different hair growth patterns and baldness.
156 citations
,
December 2012 in “Seminars in Cell & Developmental Biology” Different types of stem cells in hair follicles play unique roles in wound healing and hair growth, with some stem cells not originating from existing hair follicles but from non-hair follicle cells. WNT signaling and the Lhx2 factor are key in creating new hair follicles.
132 citations
,
January 2017 in “International Journal of Molecular Sciences” Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.
4 citations
,
January 2017 in “Development” Estrogen is important for keeping adult mouse nipple skin healthy by controlling certain cell signals.
29 citations
,
February 2019 in “Pediatric dermatology” Trichotillomania shows specific signs like black dots and uneven hair lengths but lacks certain features of alopecia areata.
5 citations
,
November 2012 in “Actas Dermo-Sifiliográficas” Comma hairs are a new sign for identifying scalp fungal infections.
72 citations
,
June 2008 in “The Journal of urology/The journal of urology” Dutasteride and finasteride do not significantly affect bone density, blood fats, or blood production, but slightly lower PSA levels and minimally impact sexual function in healthy young men.
15 citations
,
January 2019 in “Lasers in surgery and medicine” Home-use light devices can significantly reduce hair but are less effective on very dark skin and slower than professional devices.
9 citations
,
February 2022 in “Dermatology and therapy” An emollient PLUS balm with ADE-G1 significantly improved skin dryness and quality of life in cancer patients with xerosis.
July 2023 in “Clinical and Experimental Dermatology” Combining baricitinib with low-dose corticosteroids significantly improved severe hair loss in eight patients.
Anionic surfactants significantly improve the foaming of minoxidil gel shampoo.
89 citations
,
January 2007 in “Lancet Oncology” Taking 1 mg/day finasteride for hair loss significantly lowers PSA levels in men, which may affect prostate cancer screening.
68 citations
,
May 2012 in “Journal of Investigative Dermatology” The conclusion is that Fgf18 and Tgf-ß signaling could be targeted for hair loss treatments.
1 citations
,
January 2014 in “PubMed” Hair loss in a child was an early sign of Crohn's disease.
January 2011 in “Der Pharmacia Lettre” Pig oil was found to significantly promote hair growth in rats, more effectively than Minoxidil.
75 citations
,
August 2014 in “Journal of Investigative Dermatology” Aging mice have slower hair regeneration due to changes in signal balance, but the environment, not stem cell loss, controls this, suggesting treatments could focus on environmental factors.
January 1989 in “Journal of The American Academy of Dermatology” Psoriasis patients have immune cells that respond more strongly to signals and stimuli due to an intrinsic cellular defect.
51 citations
,
December 2018 in “JAMA Dermatology” PRP injections may improve skin texture and wrinkles based on patient feedback, despite no significant changes seen by dermatologists.
36 citations
,
July 1987 in “Journal of toxicology and environmental health” Rats fed heated oils had less weight gain, more organ damage, and showed signs of toxicity compared to those fed fresh oils.
1 citations
,
March 2019 in “International Journal of Current Pharmaceutical Research” The essential oils from Hedyotis corymbosa, Inula racemose, and Holostemma adakodien have significant antibacterial and antifungal properties.
March 2019 in “European Urology Supplements” Some common medications like metformin, insulin, and ACE inhibitors can lower PSA levels, while statins don't, and low dose finasteride significantly reduces PSA.
May 2016 in “Journal of Investigative Dermatology” Boosting HGF signaling could improve the creation of hair follicles in lab-made skin.
42 citations
,
May 2014 in “European Journal of Pharmacology” Ginsenoside F2 from ginseng may increase hair growth better than standard treatments by affecting cell growth signals.
41 citations
,
October 2010 in “British journal of dermatology/British journal of dermatology, Supplement” Both intense pulsed light and long-pulsed diode laser effectively reduced facial hair in women, with no significant difference in satisfaction after 6 months, but intense pulsed light was more painful.
6 citations
,
May 2014 in “Experimental Dermatology” Hair follicle regeneration is possible but challenging, especially in humans, due to the need for specific cells and a better understanding of how they signal growth.
September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” Tet1/2/3 enzymes affect hair follicle cell development by influencing BMP signaling.