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Aging reduces skin stem cell function, leading to changes like hair loss and slower wound healing.

New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.

Apple extract called procyanidin B-2 was found to greatly increase hair growth.

Actinic keratosis can lead to skin cancer, is more common in fair-skinned people, and can be reduced with sunscreen and treated effectively.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

Stem cells help remove dead cells to keep tissues healthy by balancing cell replacement and clearance.

Blocking both main energy pathways can stop hair follicle stem cell-induced skin cancer growth.

Notch signalling helps skin cells differentiate and prevents tumors.

Keratin protein production in cells is controlled by a complex system that changes with cell type, health, and conditions like injury or cancer.

MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.

Lower SMAD2/3 activation predicts more severe skin cancer.

Traditional Chinese medicinal foods may help manage long-term post-COVID symptoms.

YAP and TAZ proteins are necessary for the development of two types of skin cancer.

Cathepsin L is essential for normal hair growth and development.

Higher TGF-β signaling may increase skin cancer risk in organ transplant recipients.

MicroRNAs play a crucial role in skin and hair health, affecting everything from growth to aging, and could potentially be used in treating skin diseases.

Melanoma's complexity requires personalized treatments due to key genetic mutations and tumor-initiating cells.

Certain immune cells in the skin release a protein that stops hair growth by keeping hair stem cells inactive.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

Eicosanoids are crucial for skin health, and targeting their pathways may help treat skin conditions.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

L-PGDS has specific binding sites for its functions and could help in drug delivery system design.

Planarian regeneration begins with a specific gene activation caused by injury, essential for healing and tissue regrowth.

Skin's epithelial stem cells are crucial for repair and maintenance, and understanding them could improve treatments for skin problems.

GLP-1 receptor agonists, like Dulaglutide, Liraglutide, and Semaglutide, have potential benefits beyond the pancreas, including neuroprotection, pain suppression, cardiovascular protection, obesity management, and cancer treatment, but there are concerns about pancreatitis and pancreatic cancer risks.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

Collagen XVII is important for skin aging and wound healing.

Human hair keratin genes are similar to mouse genes and are specifically expressed in hair follicles.

Short telomeres contribute to aging and cancer, and while telomerase can delay aging, it may also promote cancer.