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This review summarizes 15 years of clinical and experimental research advancements in hidradenitis suppurativa, highlighting its recognition as a uniquely healable inflammatory skin disease but reports no new clinical results.

This article reviews knowledge-sharing efforts in pharmaceutical sciences at the University of Sorocaba, highlighting global collaboration on rational medicine use, without reporting new study results.

This article discusses the Graduate Program in Pharmaceutical Sciences at the University of Sorocaba and emphasizes collaborating internationally to improve health policies and practices but reports no new research findings.

This study found that sulforaphane-rich broccoli sprout extracts reduced UV-induced erythema by 37.7% in humans, suggesting a protective strategy against UVR damage.

In this study, researchers found that female rats exhibited more pronounced panic-related escape behavior during hypoxia, particularly in the diestrus phase, and that low-dose fluoxetine reduced this behavior, suggesting its potential for managing panic disorder symptoms related to hormonal cycles in women.

This review discusses the use of hairs and feathers as defensive tools through toxin incorporation in certain mammals and birds and reports no new experimental findings.

This study found that sebum free fatty acids may enhance the antibacterial defense of human sebaceous glands by upregulating the expression of the antimicrobial peptide hBD-2, potentially aiding in acne treatment.

This review discusses the role of defensin peptides in stem cell activation for potential skin rejuvenation therapies and reports no new clinical findings, emphasizing the need for further studies.

This review discusses the effects of photobiomodulation, particularly its potential to reduce inflammation in various conditions, but it does not report new clinical findings.

This review highlights that exosomes from adipose-derived stem cells, particularly those enriched with circ-Ash1l, can inhibit ferroptosis and reduce UVB-induced skin aging by delivering GPX4-promoting signals to damaged cells, thus offering a potential regenerative therapy for photoaged skin.

This study found that silver nanoparticles synthesized using Mitracarpus scaber extract showed potential hepatoprotective and anti-hyperplastic effects in rats, suggesting novel therapeutic strategies for managing liver injury and benign prostatic hyperplasia.

This systematic review reported that probiotics, prebiotics, synbiotics, postbiotics, and dietary supplements may improve hair density and reduce dandruff severity in individuals with scalp disorders, potentially by modifying inflammation, oxidative stress, and microbiota composition; however, variability across studies limits the strength of these conclusions.

This study found that rhesus macaques with inhibited or anxious temperaments had less alopecia, suggesting temperament may influence hair loss in these animals.

This study found that sphinganine may improve scalp health, hair quality, and reduce hair loss in males, potentially due to increased antimicrobial peptide levels and inhibition of 5-α-reductase.

This review discusses the protective roles of skin-resident immune cells in maintaining tissue homeostasis and facilitating wound healing, but reports no new experimental findings.

In this study, oral administration of wheat sprout extract significantly protected rats against skin damage caused by acrylamide exposure by enhancing antioxidant defenses, reducing oxidative stress, and preserving skin structure, highlighting its potential as a sustainable protective agent against environmental skin toxins.

In this study, O. forskahlii seed oil was found to promote hair growth in rats and exhibit anti-aging effects on human skin cells by enhancing fibroblast proliferation and inhibiting inflammation and enzyme activity, indicating potential for cosmetic use.

This study found that Ageratum conyzoides extract enhanced hair growth in mice and human follicle cells, showing potential for hormonal modulation, pathway activation, and antioxidant protection; however, further clinical studies are needed to confirm efficacy in humans.

This review explores current knowledge on fibroblast lineage specification and its impact on scar-free wound healing, noting that early fetal skin fibroblasts support regeneration, while later developmental shifts lead to fibrosis, highlighting potential strategies to reprogram adult fibroblasts for regenerative repair.

This review explores the mechanisms by which UV radiation causes skin cancer, highlighting UV-induced DNA damage and its implications for cancer prevention strategies, but reports no new findings.

This study found that a two-month antioxidant treatment significantly improved hair growth in patients with alopecia areata by enhancing antioxidant defenses and correcting trace metal imbalances.

This study evaluated the antiulcer potential of Glycyrrhiza glabra and found that its hydroalcoholic extract demonstrated dose-dependent protective effects against various ulcer models, comparable to standard drugs like omeprazole and cimetidine, by enhancing mucosal defenses and reducing stomach acid production.

This study found that red ginseng extract may stimulate hair growth in a mouse model by enhancing dermal papilla cell proliferation and activating skin antioxidant defenses.

This review discusses various amino acid-derived plant defensive compounds and highlights their potential as drug leads due to their potent antimicrobial properties, but reports no new experimental results.

This study found that CXCL12+ fibroblast subsets in mouse skin play a critical role in recruiting neutrophils and defending against S. aureus infection, with similar fibroblast activity observed in human psoriatic skin.

This study reported that, in a laboratory setting, araliadiol derived from Centella asiatica activated antioxidant pathways, mitigating urban particulate matter-induced oxidative stress and skin damage.

This review discusses the complex mechanisms regulating skin immunity to balance host defense with inflammation, but reports no new findings.

This review discusses the role of antioxidants in managing oxidative skin damage and reports no new results, emphasizing the need for understanding their mechanisms, limitations, and risks for safe use.

This article describes a framework for evaluating new health technologies by integrating quantitative evidence with qualitative assessments and using precedents to guide policy decisions, without reporting new clinical results.

This discussion of antioxidant use in pressure ulcer prevention highlights failed clinical trials but does not rule out ROS involvement or the potential efficacy of other antioxidants.