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5α reductase type 2 enzyme mutation and oxidative stress may increase androgenetic alopecia risk in Egyptians.

Gene differences may affect baldness treatment response in Korean men.

A certain mutation in the fetal alpha 5-reductase gene is linked to a higher risk of late miscarriage.

A49T gene variant linked to higher prostate cancer risk, lower hormone levels, and slightly reduced balding risk.

Longer TA repeats in the SRD5A2 gene may increase acne risk in Chinese people.

Genetic differences within ethnic groups may affect prostate cancer treatment effectiveness.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

No consistent link between genotype and phenotype in 5-α-Reductase type 2 deficiency.

Three siblings with a rare genetic condition had abnormal sexual development and chose different gender identities, needing surgery and therapy.

Gene variant linked to prostate cancer, hormone levels, and hair loss.

Early-onset baldness is linked to a higher risk of aggressive prostate cancer in African-American men, especially before age 60.

Dihydrotestosterone treatment can help penis growth in boys with 5α-reductase deficiency but doesn't fully normalize size after puberty.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Testosterone and dihydrotestosterone treatments can help with penile growth in males with 5α-reductase type 2 deficiency, with dihydrotestosterone being more effective in infancy.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.

Finasteride, a drug used for certain conditions, can cause serious side effects like sexual dysfunction, suicidal thoughts, and increased diabetes risk, and there's a need for more awareness and research about these effects.

Higher DHT in male baldness may protect against prostate cancer.

Dutasteride is more efficient than finasteride, but individual results vary.

Male pattern baldness may be linked to prostate cancer risk.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

Dutasteride is more effective than finasteride at increasing hair count and reversing hair thinning in men with hair loss, but both have similar side effects.