This study provides genomic and epigenomic insights into the white wax scale insect, highlighting high methylation levels and differential hormone profiles linked to its sexual dimorphism and developmental differences.
27 citations
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June 2023 in “Nature” In this study using genetic mouse models, researchers discovered that senescent melanocytes in nevi secrete osteopontin, which activates hair stem cells, enhancing hair growth; this process is mirrored in human hairy nevi, suggesting a potential therapeutic target for regenerative disorders.
In this case report, researchers documented a 19-year-old male professional athlete with acquired trichorrhexis nodosa, noting environmental factors like chlorine exposure during swimming may have contributed to his condition, which improved after advice on hair care changes.
19 citations
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August 1993 in “Journal of Cutaneous Pathology” In this study, researchers found that as androgenetic alopecia severity increased, the hair follicle matrix and dermal papilla's volume and cell nuclei number decreased, especially in the papilla.
7 citations
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February 2024 in “The Journal of Physiology” This study suggests that male sex and androgenic steroid use increase the risk of atrial arrhythmias in individuals with arrhythmogenic right ventricular cardiomyopathy, especially those with desmosomal gene mutations.
May 2026 in “Repository of the University of Ljubljana (University of Ljubljana)” This study analyzed the composition and cost of 50 cosmetic body scrubs for keratosis pilaris, finding that chemical exfoliants with glycolic acid may reduce symptoms by enhancing skin shedding and reducing water loss, but further clinical studies are needed to confirm their effectiveness.
The researchers observed that in cichlid fishes with different dental structures, tooth replacement accelerated more than three times following tooth extraction, alongside distinct changes in gene expression and cellular interactions over one week, providing insights into tooth regeneration mechanisms in vertebrates.
73 citations
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December 2015 in “Nature Genetics” This study found that the Dun camouflage color in horses is due to TBX3 expression, which causes uneven pigment deposition, whereas non-dun coat colors result from regulatory mutations affecting TBX3 expression.
May 2022 in “International Journal for Research in Applied Science and Engineering Technology” In this study, researchers explored the causes and treatment strategies for diffuse telogen effluvium, focusing on 60 patients with the condition linked to iron deficiency anemia, comparing the effectiveness of ferrous salts alone versus combined with Quilib lotion.
6 citations
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April 2010 in “Journal of Dermatological Science” This study observed that downregulation of laminin-511 plays an important role in hair regression during the catagen stage in mice.
January 2025 in “International Journal For Multidisciplinary Research” In this study, the researchers developed and evaluated eco-friendly poly-herbal soap strips using plant extracts from Lantana camara, Moringa Oleifera, and Corn silk, finding that the strips exhibited superior physicochemical properties and significant anti-fungal activity compared to conventional anti-fungal soaps.
June 2026 in “RCMOS - Revista Científica Multidisciplinar O Saber” This descriptive literature review suggests that rosemary essential oil may stimulate hair growth in androgenetic alopecia with effects similar to 2% minoxidil, yet highlights the need for more robust clinical trials to confirm these findings and assess complementary methods like scalp massage and high-frequency treatment.
January 2024 in “Arquivo Brasileiro de Medicina Veterinária e Zootecnia/Arquivo brasileiro de medicina veterinária e zootecnia” This study reports that treating a feline with progressive pruritus, alopecia, and FIV infection with imidacloprid and moxidectin resulted in remission of clinical signs and elimination of Demodex cati mites, as confirmed by parasitological examination and genetic sequencing.
2 citations
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December 2025 in “Nature Communications” This study found that the repressive histone mark H2AK119ub links inhibitory FGF signals with the quiescent state in hair follicle stem cells, revealing a signaling-epigenetic axis crucial for maintaining stem cell quiescence and tissue homeostasis.
March 2026 in “Dermatology and Therapy” This study identified distinct plasma miRNA profiles in alopecia areata that may aid in diagnosis and therapy, but further validation is needed to confirm these exploratory findings.
4 citations
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November 2020 in “BMC Dermatology” This study identified 374 eQTLs in scalp hair follicles associated with genes involved in metabolic, mitotic, immune processes, and responses to steroid hormones, contributing insights into genetic variation and hair traits.
October 2025 in “Open Repository of the University of Porto (University of Porto)” This report details a six-month pharmacy internship in Portugal, where the author engaged in hospital and community pharmacy settings, and discusses scientific topics including obesity medication risks and alopecia treatment options. Results and conclusions are not explicitly reported.
June 2024 in “Archives of Dermatological Research” In this study, significant upregulation of the genes SFRP2 and PTGDS was found in bald hair follicles of female pattern hair loss patients compared to non-bald follicles, suggesting these genes may be biomarkers and play a role in hair loss for this condition.
October 2023 in “Open Repository of the University of Porto (University of Porto)” Pharmacists play a crucial role in patient care and optimizing treatment outcomes.
September 2018 in “Open Repository of the University of Porto (University of Porto)” This report reviews a pharmacy internship in Oliveira de Azeméis, detailing the development of skills, practical projects on health topics, and contributions to the pharmacy’s social media presence, with no new clinical results reported.
25 citations
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January 2017 in “Steroids” This study found that the progesterone metabolite 3α-THP increased the proliferation and gene expression of human glioblastoma cells, suggesting a role in tumor progression.
This study found that Ca²⁺ signaling and peptidylarginine deiminase enzymes play a crucial role in activating neural stem cells in response to injury in zebrafish, suggesting potential therapeutic targets for CNS injuries and cancer.
April 2016 in “The Journal of Sexual Medicine” This report analyzed an FDA adverse event database and aimed to evaluate and describe post-finasteride syndrome potentially related to dutasteride, but it does not report new clinical findings.
9 citations
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November 2018 in “Journal of cosmetic dermatology” This study reports that a plant extract from Orobanche rapum can stimulate skin rejuvenation and protect cutaneous microbiota, potentially creating healthier skin.
2 citations
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August 2022 in “Emergency medicine international” This study found that a key gene signature, including FGF11, highlights the immunologic nature of keloid lesions, distinguishing them from normal fibroblasts and scars.
April 2026 in “Cellular and Molecular Immunology” In a conditional knockout mouse model, this study found that loss of the transcription elongation factor SPT6 in basal keratinocytes led to psoriasis-like skin inflammation and delayed wound healing, suggesting SPT6 plays a crucial role in maintaining epidermal immune quiescence by suppressing proinflammatory NF-κB signaling.
October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study constructed a comprehensive atlas of prenatal human skin, revealing that innate immune cells, such as macrophages, play a crucial role in skin morphogenesis by interacting with non-immune cells, influencing hair follicle formation and angiogenesis beyond their traditional immune functions.
24 citations
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October 2014 in “Cold Spring Harbor Perspectives in Medicine” Genetic research has advanced our understanding of skin diseases, but complex conditions require an integrative approach for deeper insight.
6 citations
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May 2022 in “Aging” This study found that Si Jun Zi Tang may have anti-aging effects in mice, linked to inhibition of the PI3K-AKT and P38 MAPK signaling pathways.
This study utilized a pigmented human epidermal equivalent model to incorporate melanocytes into the epidermis and found enhanced differentiation potential compared to conventional in vitro systems, reflecting in vivo cellular trajectories and highlighting melanocyte-to-keratinocyte communication pathways.