93 citations
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May 2002 in “Journal of Investigative Dermatology” This study found that chronic ultraviolet-B exposure increased skin vascularization and wrinkle formation in mice, while overexpressing the angiogenesis inhibitor thrombospondin-1 reduced these effects, suggesting angiogenesis inhibition as a potential approach to prevent photo-damage.
78 citations
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August 2014 in “Anais Brasileiros de Dermatologia” This article discusses a new global consensus on the classification of vitiligo, describing histopathological findings and outlining treatment strategies, but reports no new clinical results.
72 citations
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June 2019 in “International Journal of Cosmetic Science” This review discusses the biological properties of 18β‐glycyrrhetinic acid derived from licorice root, highlighting its potential anti-inflammatory, antioxidant, and antimicrobial benefits in treating dermatological disorders, and reports no new experimental results.
65 citations
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March 2004 in “Journal of Clinical Investigation” In this study, overexpression of ornithine decarboxylase accelerated basal cell carcinoma in Ptch1+/– mice under UVB exposure, while its inhibition reduced tumor induction, suggesting potential chemoprevention strategies in humans.
64 citations
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March 2004 in “Journal of Clinical Investigation” This study found that inhibiting the enzyme ornithine decarboxylase (ODC) prevented UVB-induced basal cell carcinomas in a mouse model, suggesting ODC is a potential target for chemoprevention strategies.
43 citations
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October 2006 in “Journal of Cell Science” In this study, researchers found that contrary to expectations, keratin 10 domains did not reduce cell proliferation and instead increased tumor development in genetically modified mice.
20 citations
,
July 2017 in “Journal of Investigative Dermatology” IL-1 receptor absence in mice leads to skin cysts and changes in immune response after UVB exposure.
14 citations
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July 2022 in “Nutrients” This review discusses new research on the role of retinoids in skin and hair health and reports no clinical results.
10 citations
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May 2021 in “Clinical, cosmetic and investigational dermatology” In this mouse study, UVA and UVB exposure led to hair follicle miniaturization, graying, and prolonged hair cycle duration, associated with changes in stem cells and increased Wnt signaling activity.
8 citations
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February 2025 in “Cell Systems” This study developed a genetic toolbox to engineer Cutibacterium acnes for dermal applications, successfully creating a strain that secretes antioxidants to reduce oxidative stress in a UV stress model.
8 citations
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June 2022 in “International Journal of Molecular Sciences” This review discusses the potential of extracellular vesicles for facial aesthetic applications, including scar reduction and skin rejuvenation, but reports no new clinical results; further research into production and mechanisms is needed.
6 citations
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March 2022 in “International journal of molecular sciences” This review explores the detrimental effects of sunlight on the skin’s circadian rhythm and photodamage, noting the potential of natural cosmeceuticals to influence this rhythm, but reports no new results.
5 citations
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September 2013 in “BMB Reports” In this study, the anti-wrinkle effect of bone morphogenetic protein receptor 1a extracellular domain was significantly greater than that of retinoic acid in a mouse model, suggesting potential for BMP antagonists in skin or hair treatments.
2 citations
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January 2023 in “Dermatologic Therapy” This study found that intradermal injections of autologous cell-free fat extract significantly improved the condition of postinflammatory hyperpigmentation patients, with high patient satisfaction and minimal adverse effects.
1 citations
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September 2024 in “iScience” In a study on mice, researchers found that exposure to artificial light environments causing circadian misalignment impaired hair growth by reducing the hair growth rate during the anagen phase, suggesting these light conditions as a potential risk factor for hair loss.
1 citations
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January 2020 in “PubMed” In this study, azelaic acid was found to enhance UVB protection in bulge cells and, when combined with minoxidil, may promote hair growth through increased Sonic hedgehog protein expression in hair follicles.
1 citations
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June 2025 in “Preprints.org” This research review found that climate change exacerbates skin conditions like photoaging, inflammatory dermatoses, and skin cancers by causing oxidative stress and inflammation, suggesting that dermatological practices should incorporate environmental and multicultural considerations to optimize patient outcomes in diverse populations.
July 2026 in “International Journal of Molecular Sciences” This review highlights that a comprehensive approach combining pharmacological, immunomodulatory, and regenerative interventions, including phototherapy enhanced with topical treatments and JAK inhibitors, appears effective and promising in the management of vitiligo by addressing its autoimmune and melanocyte-loss aspects.
November 2025 in “Pharmacological Research - Natural Products” Kesh Kanti Expert Oil promotes hair growth and protects hair health.
November 2024 in “Health Science Reports” This systematic review found that light and laser therapies, including excimer and erbium-glass lasers, generally increase hair density and diameter in various types of alopecia, with particularly notable effects in androgenic alopecia but limited efficacy in telogen effluvium.
February 2024 in “International journal of molecular sciences” This study established an animal model using UV-irradiated C57BL/6 mice to assess hair luster, reporting that UV exposure alters keratin-associated protein gene expression, and suggested potential for developing effective hair care products by evaluating treatments like oral minoxidil.
November 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that hemoglobin α expression in the epidermis is induced by oxidative stress and may function as an antioxidant, contributing to skin barrier function.
This case report presented the successful treatment of a patient with alopecia universalis using tofacitinib.
July 2023 in “International Journal of Molecular Sciences” This study found that N,N-dimethylglycine sodium salt promoted proliferation and migration of cultured human epidermal keratinocytes and had anti-inflammatory and antioxidant effects in vitro.
January 2019 in “International Journal of Plant Animal and Environmental Sciences” This study found that a 50% ethanol extract from marine green alga Chlamydomonas sp. W80 exhibited several bioactive properties, including skin lightening and hair growth promotion effects, with potential implications for bioenergy and high-value coproducts.
7 citations
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November 2016 in “Oncotarget” This study found that Lgr6+ stem cells in mice are not major initiators of UV- or chemically induced skin tumors.
20 citations
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October 2019 in “JAMA Otolaryngology–Head & Neck Surgery” This study found that the incidence of head and neck melanoma has increased by 51.1% among pediatric, adolescent, and young adult populations in North America over the past 20 years, primarily affecting males aged 15 to 39 years.
October 2022 in “Journal of advances in medicine and medical research” This study found that low-level laser therapy combined with NB-UVB therapy led to improvement in re-pigmentation for many stable vitiligo patients, with minimal and transient side effects.
5 citations
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January 2023 in “International Journal of Molecular Sciences” This review discusses the expression of circadian genes in hair follicles and their potential for monitoring circadian-rhythm-related conditions, reporting no clinical results; the authors suggest combining hair sampling with other assessments for better insight.
June 2025 in “Albus Scientia” This review discusses the role of the MC1R gene in human pigmentation and its genetic variants, reporting no new results; the authors highlight its forensic applications for phenotypic prediction.