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Melasma is now considered a skin aging disorder caused by sun exposure in people with a genetic tendency, which impacts treatment and prevention approaches.

Nrf2 helps protect skin from damage but too much can cause skin problems.

Local inflammation worsens autoimmune skin conditions by increasing antibody buildup.

Some treatments can improve skin's defense against damage, but overuse may cause other skin problems.

Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

Sunlight exposure improved a patient's skin condition, and there may be a link between a certain disease and skin growths; a leukemia treatment caused changes in hair color and growth.

Inhibiting ODC can prevent UV-induced skin cancer.

Ginsenoside Rg1 protects mouse skin from UVB damage and helps control inflammation.

Anti-TNF therapy can cause a unique type of hair loss that may get better with topical treatments without stopping the therapy.

Egg shell membrane hydrolysates can reduce wrinkles and improve skin health.

The new CoQ10 gel protects mouse skin better against aging from UV light than the old gel.

Herpes gestationis is linked to certain antigens, atopic eczema affects T cell populations and may be eased by breastfeeding, higher doses of anti-androgen treatment can improve androgenic alopecia, topical minoxidil increases hair thickness, long-term methotrexate therapy can cause liver fibrosis in psoriasis patients, and Lichen Sclerosus et Atrophicus patients aren't at higher risk for autoimmune disorders.

Looking older on the outside might be linked to aging faster on the inside and can be affected by lifestyle choices and health risks.

Liposomes could improve how skin care products work but are costly and not very stable.

The environment around melanocyte stem cells is key for hair regeneration and color, with certain injuries affecting hair color and potential treatments for pigmentation disorders.

ATP increases melanin production in skin after UV exposure, with the P2X7 receptor being crucial for this process.

Genetic discoveries are key for understanding, diagnosing, and treating inherited hair and nail disorders.

Some drugs can cause skin and hair color changes, often reversible when the drug is stopped.

Local skin glucocorticoid production is crucial for healthy skin, and its disruption can lead to skin diseases.

Redheaded people have higher levels of a vitamin D precursor, suggesting red hair may be an adaptation for better vitamin D synthesis in areas with less sunlight.

A girl with symptoms like an autoimmune disorder actually had HIV and a fungal infection, which was hard to diagnose and treat, leading to her death.

Herbal nano-formulations show potential for effective skin delivery but need more research.

The document concludes that the discussed biological mechanisms and potential therapies are not related to hair loss or hair growth.

Carvone helps treat skin issues by reducing melanin and stopping harmful cell growth.

SCF and ET-1 together significantly increase skin pigmentation and melanin production.

Different types of stem cells and their environments are key to skin repair and maintenance.

Certain genes control the color of human hair by affecting pigment production.

Applying a specific inhibitor lightens skin and hair color.

EdnrB signaling helps melanocyte stem cells regenerate and could be targeted to treat pigmentation issues.

OCT binds strongly to hair sheath cells and may affect skin and hair growth with fewer side effects than vitamin D3.