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Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Regenerative therapies show promise for treating vitiligo and alopecia areata.

ATP increases melanin production in skin after UV exposure, with the P2X7 receptor being crucial for this process.

Vitamin D made by the skin plays a role in immune defense and skin health, and more research is needed to understand its full effects.

ceRNA networks offer potential treatments for skin aging and wound healing.

Some alternative therapies for vitiligo show promise but need more research.

Low-level laser therapy combined with NB-UVB is a safe and potentially effective treatment for stable vitiligo.

Fat-derived stem cells and their secretions show promise for treating skin aging and hair loss.

Targeting ornithine decarboxylase can help prevent skin cancer.

Azelaic acid helps protect hair cells from UV damage and encourages hair growth by increasing certain gene expressions and proteins.

BMPR1a-ECD reduces wrinkles much more effectively than retinoic acid.

Inhibiting ODC can prevent UV-induced skin cancer.

Inhibiting ornithine decarboxylase may help prevent certain skin cancers.

A3B5 can reduce skin pigmentation and slow melanoma growth.

Vitamin A is important for healthy skin and hair, influencing hair growth and skin healing, but UV light reduces its levels.

UV exposure causes hair thinning, graying, and changes in hair growth cycles in mice.

Tiny particles called extracellular vesicles show promise for skin improvement and anti-aging in facial care but face challenges like low production and lack of research.

Noncrosslinked hyaluronic acid helps human hair cells grow and could be a potential hair loss treatment.

Combining narrow-band ultraviolet B light and stem cell transplantation helps repigmentation in vitiligo by maintaining calcium balance in mice.

Fat tissue vesicles protect skin from UV damage better than stem cell vesicles.

Ectoin helps prevent cortisone-induced skin problems and supports skin health.

Skin cells and certain hair follicle areas produce hemoglobin, which may help protect against oxidative stress like UV damage.

Ginseng, especially its component ginsenosides, can promote hair growth, reduce hair loss, and potentially treat conditions like alopecia by affecting cell pathways and cytokines.

B6.Cg-Tyr c−2J Hr hr /J mice have a stronger delayed sunburn reaction and are good for UV research.

The reconstructed skin model from hair follicles functions like human skin in processing chemicals and can be used to test ingredient safety.

Cell death shapes skin stem cell environments, affecting inflammation, repair, and cancer.

Caffeine applied to the scalp can protect hair follicles from UV damage.

Melatonin receptors in hair follicles help regulate hair growth and could treat hair loss.

Curcumin applied to the skin can start hair growth in mice.

Pulsed red light boosts collagen and energy in cells faster than continuous red light.