research Inherited Ichthyosis: Syndromic Forms
Understanding the genetics of rare inherited ichthyosis syndromes is key for better treatments and genetic counseling.
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research Wnt/β-Catenin Signaling Pathway Activates Melanocyte Stem Cells In Vitro and In Vivo
The Wnt/β-catenin pathway can activate melanocyte stem cells and may help regenerate hair follicles.
research Interaction Between Stem Cell Factor and Endothelin-1: Effects on Melanogenesis in Human Skin Xenografts
SCF and ET-1 together significantly increase skin pigmentation and melanin production.
research Stereocontrolled Synthesis of All Eight Stereoisomers of the Putative Anti-Androgen Cyoctol
Scientists made all eight versions of a compound called cyoctol, but found it's not an anti-androgen and it fully breaks down in the skin.
research Adam10 Haploinsufficiency Causes Freckle-Like Macules in Hairless Mice
A mutation in the Adam10 gene causes freckle-like spots on Hairless mice.
research Alterations in Transcriptome and Antioxidant Activity of Naturally Aged Mice Exposed to Selenium-Rich Rice
Eating selenium-rich rice improved antioxidant activity and signs of aging in mice.
research Protective Effects of Finasteride on the Pulmonary Immune Response in a Combined Model of Trauma-Hemorrhage and Polymicrobial Sepsis in Mice
Finasteride helps reduce lung inflammation and damage after trauma and infection.
research Synthesis, Anticancer, and Molecular Docking Studies of 2-(4-Chlorophenyl)-5-Aryl-1,3,4-Oxadiazole Analogues
The compound 4c showed strong potential as an anticancer agent.
research Evaluation of Apoptosis Regulatory Markers in Androgenetic Alopecia
Apoptosis may contribute to hair loss in androgenetic alopecia.
research Low-Level Light Therapy for Cosmetics and Dermatology
Low-Level Light Therapy is effective for skin rejuvenation, wound healing, and hair growth, with mild side effects.
research Connubial Androgenetic Alopecia
Hamilton scale imprecise, hair shaft diameter decreases, stem cell transplant regrows hair, ECP ineffective for alopecia areata universalis.
research The Eosinophilia-Myalgia Syndrome
Eosinophilia-myalgia syndrome, linked to contaminated L-tryptophan supplements, caused severe symptoms and some deaths, with long-term effects in survivors.
research Autoimmune Skin Disorders
The document concludes that autoimmune skin disorders are treated with corticosteroids and immunosuppressive drugs.
research Comparison of Three Different Lactic Acid Bacteria-Fermented Proteins on RAW 264.7 Osteoclast and MC3T3-E1 Osteoblast Differentiation
Fermented soy protein may help prevent bone loss by affecting bone cell activity.
research Skin Involvement in Systemic Lupus Erythematosus: A Review Article
Skin problems are common in lupus, often appearing first, with various types and treatments, and careful monitoring is important for diagnosis and management.
research Effect of Decellularisation Methods on Methacryloyl-Substituted Placental ECM Hydrogels
PlacMA hydrogels from human placenta are versatile and useful for cell culture and tissue engineering.
research Androgenetic Alopecia in Women
Female hair loss is often hereditary and can be treated with medication, hair transplants, and lasers.
research Neuroimmunology of Stress: Skin Takes Center Stage
Stress can worsen skin and hair conditions by affecting the skin's immune response and hormone levels.
research The Human Tri-Peptide GHK and Tissue Remodeling
The peptide GHK-Cu helps heal and remodel tissue, improves skin and hair health, and has potential for treating age-related inflammatory diseases.
research The Role of Tight Junctions in Skin Barrier Function and Dermal Absorption
Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.
research Androgenetic Alopecia: An Update
Minoxidil and finasteride effectively treat hair loss.
research Aging of the Hair Follicle Pigmentation System
Hair grays due to oxidative stress and fewer functioning melanocytes.
research From Neural Crest Cells to Melanocytes: Cellular Plasticity During Development and Beyond
Melanocyte development from neural crest cells is complex and influenced by many factors, and better understanding could help treat skin disorders.
research Bioactive Anti-Inflammatory Antibacterial Hemostatic Citrate-Based Dressing With Macrophage Polarization Regulation for Accelerating Wound Healing and Hair Follicle Neogenesis
A special dressing called FEA-PCEI can speed up wound healing, reduce scars, and help grow new hair follicles, but only at the right dosage.
research Treatment of Generalized Lichen Planus With Alefacept
Alefacept may effectively treat severe lichen planus, with patients showing significant improvement and no side effects.
research Advances in the Management of Alopecia Areata
New treatments for severe hair loss often fail, but some patients see hair regrowth with specific therapies, and treatment should be tailored to the individual's situation.
research Ultrasound-Activated Particles as CRISPR/Cas9 Delivery System for Androgenic Alopecia Therapy
Scientists have created a new hair loss treatment using ultrasound to deliver gene-editing particles, which resulted in up to 90% hair regrowth in mice.
research Noncoding dsRNA Induces Retinoic Acid Synthesis to Stimulate Hair Follicle Regeneration via TLR3
Noncoding dsRNA boosts hair growth by activating TLR3 and increasing retinoic acid.
research Topical Immunotherapy in Alopecia Areata
Topical immunotherapy, especially with DPCP, is effective for treating severe alopecia areata.
research Differential Diagnosis of Hair Loss in Children
The document concludes that early diagnosis and treatment are crucial for children with hair loss to prevent permanent damage, although not all conditions can be effectively treated.