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Spironolactone harms fish reproduction and is more potent in fish than invertebrates, needing environmental monitoring.

Acitretin is effective for severe psoriasis and can be used long-term due to no immunosuppression, but must be carefully monitored for side effects and is not for pregnant women.

Particle properties affect drug retention and release in minoxidil foams, with lipid nanoparticles having higher loading capacity.

Longer contact time increases minoxidil absorption, but doesn't affect metabolism.

Some treatments like methotrexate with prednisone might help juvenile morphea, but more research is needed to confirm.

Hibiscus rosa-sinensis may help treat various health issues and promote hair growth, but more research is needed for safety.

FGF9 controls which receptors it binds to through a process where two FGF9 molecules join, and changes in FGF9 can lead to incorrect receptor activation.

The document concludes that accurate diagnosis of hair loss in children is crucial due to limited treatment options and the condition's psychological impact.

Most pregnant women experience skin changes like darkening and itching, while serious skin conditions are rare but need early treatment.

Ganoderma lucidum may help treat enlarged prostate in rats.

Using defensins to activate stem cells may improve skin aging signs without causing inflammation.

Permanent hair loss from cicatricial alopecia is treated by reducing inflammation and managing symptoms, but regrowth in scarred areas is unlikely.

Nanoemulsions improve stability and delivery of active ingredients in cosmetics for skin and hair care.

Cyclodextrins improve finasteride's solubility and bioavailability for hair loss treatment.

Minoxidil-coated microbubbles with sonication effectively enhance hair growth.

Probe detects finasteride with high selectivity and low detection limit.

About 15% of US Army personnel use hair products containing hormone or placenta, with higher usage among non-whites, females, and enlisted personnel.

Genetic discoveries are key for understanding, diagnosing, and treating inherited hair and nail disorders.

St. John's Wort extract and oil safety in cosmetics is unclear; more data needed on photosensitization, toxicity, and human irritation.

The nanoparticles improved hair growth and enlarged hair bulbs.

New physical methods like electrical currents, ultrasound, and microneedles show promise for improving drug delivery through the skin.

Recognizing and treating skin symptoms in essential thrombocythemia is crucial for patient quality of life.

People with Lichen planopilaris are more likely to have certain autoimmune and endocrine disorders but less likely to have conditions like allergies and diabetes.

Vesicular carriers like liposomes may improve cosmetic skin treatment delivery and effectiveness but need more human research.

Nano-sized lipid particles increase dexamethasone's skin penetration and create a reservoir in the skin layers.

PRP shows promise for improving facial wrinkles, skin elasticity, and hair growth, but more research is needed to standardize its use and understand its effects.

Nanoemulsions with minoxidil and clove oil effectively target hair follicles for better alopecia treatment.

Acne lesions start with changes in hair follicles and increase in inflammation, suggesting a cycle that could affect treatment strategies.

A new gel containing minoxidil can treat hair loss effectively, potentially reducing side effects and improving treatment.

Encapsulated Garcinia mangostana extract in cream penetrates skin better than other forms.