research Genetic Ablation of the CDP/Cux Protein C Terminus Results in Hair Cycle Defects and Reduced Male Fertility
Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.
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research Androgen Antagonists in Androgen Target Tissues
Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.
research Hirsutism: Diagnosis and Treatment
The document concludes that proper diagnosis and combined treatments are key for hirsutism management, and weight loss may help overweight patients.
research New Dimensions in Hirsutism
Laser hair removal is safe and effective for fair-skinned people with dark hair, and using eflornithine with laser treatments can improve results.
research Pigmentation and Pregnancy: A Study on Skin Changes
Most skin changes during pregnancy are harmless and moles don't significantly change, but many women experience pigmentation changes due to hormones and sun exposure.
research Progestogens in Menopausal Hormone Therapy
Progestogens are essential in menopausal hormone therapy to prevent uterine cancer and must be chosen carefully based on individual needs.
research Alternative Medicine for Hair Loss
Some natural remedies may help with hair regrowth, but more research is needed to confirm their effectiveness and safety.
research Precocious Puberty: A Case Report
Early diagnosis and treatment with Leuprolide are key for children with precocious puberty.
research A 14-Year-Old Female with Primary Amenorrhea
A 14-year-old girl with no menstrual period was diagnosed with Swyer Syndrome and treated for a related cancer risk.
research Steroid Sulfatase: Molecular Biology, Regulation, and Inhibition
The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.
research Fetal Alcohol Syndrome: Current Status of Pathogenesis
The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.
research Estrogens and Aging Skin
Estrogen therapy can reduce skin aging but has cancer risks.
research Androgens and Androgen Receptor Action in Skin and Hair Follicles
Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.
research 5α-Reductase Isozymes and Androgen Actions in the Prostate
5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.
research Medical Treatment of Hirsutism
The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.
research Androgen Receptors And Their Biology
Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.
research Hormone Replacement Therapy for Women with Premature Ovarian Insufficiency: A Comprehensive Review
The review recommends hormone replacement therapy for women with premature ovarian insufficiency to manage symptoms and protect health, with specific approaches for different groups.
research Nonclassic Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency: Pathophysiology, Diagnosis, and Treatment
The document concludes that Nonclassic Congenital Adrenal Hyperplasia requires personalized treatment plans to manage symptoms and fertility, with glucocorticoids being a common therapy.
research Sulfatase Inhibitors: A Patent Review
The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.
research Treatment of Hirsutism and Acne with Cyproterone Acetate
Cyproterone acetate is effective for treating hirsutism and acne but less so for hair loss, with side effects similar to birth control pills.
research Roles of Wnt7a in Embryo Development, Tissue Homeostasis, and Human Diseases
Wnt7a protein is crucial for development and tissue maintenance and plays varying roles in diseases and potential treatments.
research Mrp4, A New Mitogen-Regulated Protein/Proliferin Gene; Unique in This Gene Family for Its Expression in the Adult Mouse Tail and Ear
A new gene, mrp4, is found in mice and may play a unique role in hair follicle development in tails and ears.
research The Evaluation and Management of Hirsutism
Hirsutism in women often indicates a hormonal imbalance and can be managed with a combination of hormonal treatments and hair removal methods.
research Melatonin Supplement Induced Hair Follicle Development in Offspring Rex Rabbits
Melatonin given to pregnant rabbits improved their babies' fur quality.
research The E6/E7 Oncogenes of Human Papillomavirus and Estradiol Regulate Hedgehog Signaling Activity in a Murine Model of Cervical Cancer
HPV genes and estradiol increase a cancer-related signaling pathway, which may be targeted for cervical cancer treatment.
research Novel Progestogenic Androgens for Male Contraception: Design, Synthesis, and Activity of C7 Alpha-Substituted Testosterone
New testosterone analogs show promise for male contraception with better activity and potentially fewer side effects.
research Genetics and Pathophysiology of Congenital Adrenal Hyperplasia
The document concludes that patient outcomes for Congenital Adrenal Hyperplasia are often not ideal because of poor management and a need for better diagnosis and treatment methods.
research Pharmacodynamic Evaluation: Endocrinology
The conclusion is that endocrinology significantly impacts medicine with various common medications used for treatment.
research Skin Abnormality and Hair Loss: The Reproductive Endocrinological Viewpoint
Hormonal imbalances can cause skin and hair problems in women, and treatments that block male hormones can help.
research Drug Safety Evaluation of Exemestane
Exemestane is effective and safe for treating certain breast cancers, with mild side effects, but needs more research on long-term effects.