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Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

Mutations in the androgen receptor gene cause Androgen Insensitivity Syndrome, affecting sexual development.

Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.

The document concludes that combination therapy is most effective for treating excessive hair growth in women with idiopathic hirsutism, and more research is needed to understand the condition.

The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

Removing part of the vitamin D receptor stops vitamin D from working properly.

Menopause can lead to skin and hair problems due to hormonal changes, but hormone replacement therapy might help slow these effects.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Estrogen replacement can improve skin health in menopausal women but doesn't reverse sun damage or prevent hair loss.

Coal tar shampoos, salicylic acid, and topical corticosteroids are effective for scalp psoriasis, with Vitamin D3 analogues also showing benefits; severe cases may require stronger medication with more risks.

Exposure to finasteride in the womb caused lasting reproductive issues in male rats.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

The document concludes that proper diagnosis and a multidisciplinary approach are crucial for managing Congenital Adrenal Hyperplasia effectively.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

Low doses of mixed chemicals cause permanent reproductive malformations in male rats.

Some Middle Eastern plants may help treat diabetes and could be alternatives to current drugs, but more research is needed.

Progesterone and related compounds may help control seizures linked to the menstrual cycle but have limitations that need addressing.

Eyebrow loss has many causes and requires accurate diagnosis for proper treatment.

A new hair loss treatment uses tiny needles to deliver a drug-loaded lipid carrier, promoting hair growth more effectively than current treatments.

Menopausal women have higher androgen levels, which can cause symptoms like facial hair growth and low sexual desire.

Taking too many vitamin and mineral supplements can cause serious health problems.

Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Some skin medications can harm male fertility, but they don't seem to cause birth defects from father's exposure.

COVID-19 may harm male fertility and damage the reproductive system.

The document concludes that low-dose oral contraceptives and hormonal therapies can manage perimenopause symptoms and reduce some health risks, but lifestyle changes and disease screening are also important.