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While PCOS might increase the risk of heart disease, there's not strong evidence to prove it causes earlier heart problems.

Testosterone therapy increases bone density in older men with low testosterone levels.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

The bulletin provides guidelines for diagnosing and managing PCOS, suggesting weight loss, hormonal contraceptives, and diabetes screening, with clomiphene for infertility and various treatments for excess hair.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

Most women referred for excess male hormone symptoms had polycystic ovary syndrome (PCOS), with other conditions being less common.

Itraconazole is potentially effective for treating invasive aspergillosis, but more research is needed.

The guide recommends specific methods for diagnosing PCOS and various treatments for its symptoms, while considering the health impacts on adolescents.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Fat tissue-derived cells show promise for repairing body tissues, but more research and regulation are needed for safe use.

Removing part of the vitamin D receptor stops vitamin D from working properly.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

The NAMS 2014 recommendations guide healthcare providers on treating health issues in midlife women, emphasizing individualized care and informed decision-making.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Finasteride doesn't effectively treat hair loss in postmenopausal women.

Tofacitinib is effective and safe for severe hair loss, but full regrowth is less likely after 10 years of hair loss.

The report recommends personalized treatment for women's sexual dysfunctions and more research on effective therapies.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.

Melatonin may help with sleep issues, depression, and cancer, but more research is needed.

Diagnosing PCOS in teenagers is challenging and should use strict criteria to avoid misdiagnosis and unnecessary worry.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

Androgens can both increase and decrease hair growth in different parts of the body.

Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

Ruxolitinib effectively regrows hair in most patients with severe hair loss.

Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.

Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.