research Effect of Finasteride and/or Terazosin on Serum PSA: Results of VA Cooperative Study #359
Finasteride reduces PSA levels, terazosin doesn't affect them, and tracking prostate cancer in patients taking finasteride could be difficult.
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research Metabolism of Minoxidil, a New Hypotensive Agent: Biotransformation Following Oral Administration to Rats, Dogs, and Monkeys
Minoxidil metabolizes similarly in monkeys and humans, but differently in dogs and rats.
research Progestogen-Only Pill Associates with False-Positive Aldosterone/Renin Ratio Screening Test
The birth control pill with only progestogen can cause a false alarm in a hormone test.
research Hyperandrogenism Caused by Leydig Cell Tumor of the Ovary
A woman's excess male hormone symptoms were caused by a rare benign tumor in her ovary.
research Tumor Regression Predicts Higher Risk of Sentinel Node Involvement in Thin Cutaneous Melanomas
Shrinking skin cancer increases the chance of cancer in nearby lymph nodes.
research Ichthyosis Follicularis, Alopecia, and Photophobia Syndrome in a Saudi Child: A Case Report
An 8-year-old Saudi boy was diagnosed with a rare genetic disorder causing hair loss, skin issues, and light sensitivity.
research Insulin Resistance, Nitric Oxide, and Fibrinogen Levels in White Hirsute Women: Defining a New Paradigm Based on Translational Research
White hirsute women with PCOS have higher insulin resistance, but similar nitric oxide and fibrinogen levels compared to those with idiopathic hirsutism.
research JAK Inhibitors and Alopecia Areata
JAK inhibitors help regrow hair in alopecia areata patients, improving their quality of life.
research Synthesis, Characterization and Evaluation of 5α, 6β-Dihalo Androsterone Derivatives as 5α-Reductase Inhibitors
Compound 7b is a promising candidate for treating benign prostatic hyperplasia and prostate cancer.
research Development and Optimization of Finasteride-Cinnamon Oil-Loaded Ethanol-Free Microemulsions for Transdermal Delivery
The optimized microemulsion with cinnamon oil effectively delivers finasteride through the skin without damaging hair.
research Subacute Cutaneous Lupus Erythematosus Presenting as Erythroderma
A woman with subacute cutaneous lupus erythematosus had widespread skin symptoms triggered by medication and sunlight, which improved with specific treatments.
research Hair Loss: A Harbinger of Morbidities to Come
Early hair loss in men and women may indicate a higher risk of heart disease and metabolic problems.
research Dual Deficiency of Melatonin and Dihydrotestosterone Promotes Stromal Cell Damage and Mediates Prostatitis via the cGAS-STING Pathway in Sleep-Deprived Mice
Lack of sleep in mice leads to prostatitis by reducing certain hormones and activating an inflammatory pathway, which can be temporarily fixed with normal sleep.
research Effects of In Utero Exposure to D-004, a Lipid Extract from Roystonea Regia Fruits, in the Male Rat: A Comparison with Finasteride
D-004 may be a natural alternative to finasteride for treating enlarged prostate and male baldness.
research A 1.6cm Androgen Secreting Ovarian Leydig Cell Tumor Evades Detection on Multiple Imaging Modalities
A woman's small ovarian tumor causing high androgen levels was missed by several scans but found during surgery.
research Clinical Review of Ejaculatory Dysfunction
The review suggests new ways to classify ejaculation problems and recommends different treatments based on the type of issue.
research Notes, Short Comments, And Answers To Correspondents
The document discusses various public health initiatives and societal issues, emphasizing early intervention and support.
research A Fixed-Dose Combination of Finasteride and Tadalafil (Entadfi) for BPH
Entadfi, a mix of finasteride and tadalafil, is used for BPH.
research Adverse Side Effects of 5α-Reductase Inhibitors Therapy: Persistent Diminished Libido, Erectile Dysfunction, and Depression in a Subset of Patients
Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.
research Impact of Ustekinumab on Quality of Life and Sexual Difficulties Associated with Psoriasis: Results from Phase III Clinical Trials
Ustekinumab significantly improved sexual function and quality of life for people with moderate to severe psoriasis.
research Callus Production and Analysis of Isoflavonoids and Some Terpenes from Bituminaria Bituminosa
The research found a way to grow plant tissue and analyze compounds in Bituminaria bituminosa, which is promising for hair restoration treatments.
research Neuropsychological Assessment in Elderly Men with Benign Prostatic Hyperplasia Treated with Dutasteride
Dutasteride does not impair mental function in elderly men with enlarged prostate.
research Osler’s Phenomenon: Misdiagnosing Cushing’s Syndrome
Doctors often diagnose Cushing's syndrome late, which worsens symptoms; earlier detection is needed.
research Novel Inhibitors of 5α-Reductase
New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.
research Phenolic Composition, Enzyme Inhibitory, and Antioxidant Activity of Bituminaria Bituminosa
The water extract of Bituminaria bituminosa, high in phenolic compounds, shows strong antioxidant and enzyme inhibitory potential.
research A Falling Out Following Minoxidil: Telogen Effluvium
A man lost a lot of scalp hair quickly after stopping minoxidil, but it grew back with mild male pattern baldness.
research Comment on 'The Post-Finasteride Syndrome: Possible Etiological Mechanisms and Symptoms'
Some men experience persistent sexual, neurological, and psychological symptoms after stopping finasteride, but evidence of permanent damage is inconclusive.
research Localization of Plasminogen Activator Inhibitor Type 2 in Hair and Nail: Implications for Terminal Differentiation
PAI-2 helps in the maturation and protection of hair and nail cells.
research Prevalence of Metabolic Syndrome and Its Components Among Men With and Without Clinical Benign Prostatic Hyperplasia: A Large, Cross-Sectional, UK Epidemiological Study
Men with benign prostatic hyperplasia are more likely to have metabolic syndrome than those without it.
research Optimization of Microstructured Biodegradable Finasteride Formulation for Depot Parenteral Application
Improved finasteride formula allows slow, sustained release and better absorption for patients.