research Patients With a Large Prostate Show a Higher Prevalence of Androgenetic Alopecia
Large prostate links to more hair loss, but age of onset doesn't affect it.
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research Transdermal Film-Loaded Finasteride Microplates to Enhance Drug Skin Permeation: Two-Step Optimization Study
Optimized film improves finasteride skin absorption and treatment efficiency.
research Long-Term Use of 5α-Reductase Inhibitors and the Risk of Male Breast Cancer
Taking 5α-reductase inhibitors does not significantly increase the risk of breast cancer in men.
research Novel Inhibitors of 5α-Reductase
New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.
research A Review on Steroidal 5α-Reductase Inhibitors for Treatment of Benign Prostatic Hyperplasia
New treatments for enlarged prostate are being developed, some of which may be more effective than current medications.
research Development of a Doxazosin and Finasteride Transdermal System for Combination Therapy of Benign Prostatic Hyperplasia
Researchers created a skin patch that delivers two drugs for treating enlarged prostate, which may improve patient use and dosage control.
research Plasma Androsterone/Epiandrosterone Sulfates as Markers of 5α-Reductase Activity: Effect of Finasteride in Normal Men
Finasteride effectively lowers specific hormone levels, helping monitor treatment progress.
research Impact of Alpha Blockers, 5-Alpha Reductase Inhibitors, and Combination Therapy on Sexual Function
Medications for enlarged prostate can cause sexual side effects like reduced libido, erectile dysfunction, and ejaculatory problems.
research Separation of Finasteride and Analogues
Finasteride and analogues separated using LC-MS-MS technique.
research Pharmacokinetic Interaction Between Finasteride and Terazosin, but Not Finasteride and Doxazosin
Finasteride interacts with terazosin, but not doxazosin; caution needed.
research Six Weeks Finasteride Monotherapy Before TURP: Does It Improve Quality of Life in Early Postoperative Period?
Finasteride before TURP reduces blood loss and slightly improves early postoperative quality of life.
research Health Issues Unique to the Aging Man
Aging men face unique health issues like erectile dysfunction, prostate problems, and baldness.
research Biotransformation of Finasteride (MK-0906) by Selenastrum Capricornutum (Green Algae)
Green algae can break down finasteride, reducing environmental harm.
research Medical Management of Benign Prostatic Hyperplasia
Alpha-blockers and 5-alpha reductase inhibitors are main treatments for BPH, with new support for phosphodiesterase-5 inhibitors and beta-3 agonists.
research Comments Concerning the Real Risk of Sexual Adverse Events Secondary to the Use of 5-Alpha-Reductase Inhibitors
The document concludes that the risk of sexual side effects from 5-alpha-reductase inhibitors is low and often temporary, but more research is needed on potential permanent effects.
research Association of Androgenetic Alopecia with Benign Prostatic Hyperplasia: A Case Control Study
Hair loss linked to prostate enlargement; stress and family history important factors.
research Finasteride 5mg and Sexual Side Effects: How Many Are Related to a Nocebo Phenomenon?
Knowing about finasteride's sexual side effects increases reported dysfunction.
research Epidemiology and Treatment Modalities for the Management of Benign Prostatic Hyperplasia
More men are getting benign prostatic hyperplasia, and there are many treatments, from medication to surgery, with new methods being developed.
research Effects of 5-Alpha Reductase Inhibitors on Erectile Function, Sexual Desire, and Ejaculation
5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.
research What Do We Know About Phytotherapy of Benign Prostatic Hyperplasia?
Some plant-based treatments can help with benign prostatic hyperplasia symptoms, but more research is needed to confirm their safety and effectiveness.
research Pharmacological Interventions for Treating Chronic Prostatitis/Chronic Pelvic Pain Syndrome
Some drugs may reduce prostatitis symptoms short-term with few side effects.
research LY191704: A Selective, Nonsteroidal Inhibitor of Human Steroid 5 Alpha-Reductase Type 1
LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.
research Incomplete Recovery of Erectile Function in Rats After Discontinuation of Dual 5-Alpha Reductase Inhibitor Therapy
Rats had lasting erectile problems after stopping a certain medication.
research Current Treatment of Benign Prostatic Hyperplasia
TURP is the best treatment for BPH, but some patients prefer medications like alpha-blockers and finasteride.
research 5α-Reductase Inhibitors: Progress and Therapeutic Potential
5α-reductase inhibitors help treat disorders caused by DHT and have potential for future therapies.
research Insulin Resistance, Nitric Oxide, and Fibrinogen Levels in White Hirsute Women: Defining a New Paradigm Based on Translational Research
White hirsute women with PCOS have higher insulin resistance, but similar nitric oxide and fibrinogen levels compared to those with idiopathic hirsutism.
research Impact of Ustekinumab on Quality of Life and Sexual Difficulties Associated with Psoriasis: Results from Phase III Clinical Trials
Ustekinumab significantly improved sexual function and quality of life for people with moderate to severe psoriasis.
research 5α-Reductase Activity in the Prostate
Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.
research Finasteride
Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.
research Role of 5α-Reductase in Health and Disease
5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.