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The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Anticancer drugs are increasingly found in surface waters, and their long-term environmental effects are not well understood, requiring better testing methods.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

The NAMS 2014 recommendations guide healthcare providers on treating health issues in midlife women, emphasizing individualized care and informed decision-making.

Finasteride doesn't effectively treat hair loss in postmenopausal women.

The report recommends personalized treatment for women's sexual dysfunctions and more research on effective therapies.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Diagnosing PCOS in teenagers is challenging and should use strict criteria to avoid misdiagnosis and unnecessary worry.

Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.

Male and female skin differ in many ways, which could lead to gender-specific skin treatments.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.

Menopause can lead to skin and hair problems due to hormonal changes, but hormone replacement therapy might help slow these effects.

Experts recommend thorough medical, sexual, and psychosocial assessments for women's sexual dysfunctions, and suggest individualized treatment plans with regular check-ups. They also mention potential use of estrogen and androgen therapy, but with caution due to safety concerns.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Women with PCOS have heart-related issues not because of obesity, but due to insulin resistance and low adiponectin levels.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Most women with hirsutism or androgenic alopecia had polycystic ovaries, especially if they had irregular periods.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

Obesity is linked to various skin problems and may increase the risk of skin cancer.

Finasteride may help some male chronic pelvic pain patients, but more research needed.

Finasteride effectively treats baldness but may cause sexual side effects.

Testosterone's muscle-building effects do not require its conversion to DHT.

Dihydrotestosterone gel improved well-being and sexual function in older men without negatively affecting prostate health.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

A new gene mutation causes female pseudohermaphroditism due to glucocorticoid resistance.

Spironolactone most effective for hirsutism, but has side effects.

Finasteride improves hair loss in women with hyperandrogenism.