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The MAPK/ERK pathway is crucial in controlling cell growth and death in finasteride-induced hypospadias.

Finasteride affects male rat genitalia development, causing abnormalities during specific pregnancy days.

Penile strangulation from hair can cause severe harm but can be treated if caught early.

Using buccal mucosa for hypospadias repair in children is effective and reduces complications.

A 13-year-old with 46 XY DSD had ambiguous genitalia due to incomplete masculinization.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

The junction of the inner and outer prepuce with good blood flow is best for vascular pedicle flaps.

Micro-CT helps identify suitable areas for surgical procedures based on blood vessel distribution in hypospadias-affected rats.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

Pre-operative hormone treatment for hypospadias surgery might improve outcomes, but more research is needed to confirm.

The junction of the inner and outer prepuce with good blood flow is ideal for surgical flaps.

Disrupting β-catenin signaling in certain cells causes anorectal malformations.

Using a laser to remove hair in the urethra after hypospadias repair is effective and minimally invasive.

PRP is safe but not more effective than a placebo for treating mild to moderate erectile dysfunction.

Platelet-rich plasma shows promise for treating various female reproductive health issues but requires more research.

Itraconazole may cause low platelet and white blood cell counts.

Cell transplantation faces challenges in genitourinary reconstruction, but alternative tissue sources and microencapsulation show promise.

Dihydrotestosterone gel before hypospadias surgery led to less scarring but raised concerns about potential psychological effects and skin changes.

Basonuclin 2 is vital for the development of facial bones, hair follicles, and male germ cells in adult mice, and its absence can lead to dwarfism and abnormal follicles.

Men with urinary symptoms are more likely to have erectile dysfunction, and there's a debate about research methods and authorship ethics.

Saw palmetto can help with prostate issues and may promote hair growth.

The document concludes that proper diagnosis and a multidisciplinary approach are crucial for managing Congenital Adrenal Hyperplasia effectively.

Researchers created a skin patch that delivers two drugs for treating enlarged prostate, which may improve patient use and dosage control.

International medical graduates outperformed U.S. graduates on an internal medicine exam.

International medical graduates outperformed U.S. graduates on an internal medicine exam.

High doses of fluconazole can cause reversible hair loss.

Hormones significantly affect women's sexual function, and more research is needed to improve treatments for sexual dysfunction with minimal side effects.

Flutamide-induced hypospadias in rats slows down early wound healing.

Created method to measure doxazosin mesylate and finasteride together.