research Loss of Epidermal Melanin Unit Integrity in Human Skin During Melanoma Genesis
Melanoma development can be linked to the breakdown of skin's melanin-producing units.
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research Targeted Deletion of Crif1 in Mouse Skin Epidermis Impairs Skin Homeostasis
Removing the Crif1 gene in mouse skin disrupts skin balance and hair growth.
research Hair in Health and Disease: An Introduction
Hair health depends on various factors and hair loss can significantly affect a person's well-being; understanding hair biology is key for creating effective hair care treatments.
research Induced Pluripotent Stem Cell Derived Keratinocyte Differentiation from Reprogrammed Blood Cells
Blood cells turned into stem cells can become skin cells similar to normal ones, potentially helping in skin therapies.
research Mediator 1 Ablation Induces Enamel-to-Hair Lineage Conversion in Mice Through Enhancer Dynamics
Removing Mediator 1 from certain mouse cells causes teeth to grow hair instead of enamel.
research Anatomical Mapping and Density of Merkel Cells in Skin and Mucosae of the Dog
Dogs have varying numbers of touch-sensitive Merkel cells in different skin areas, with most in the oral mucosa and facial skin, unrelated to age, sex, breed, or color.
research Treatment of Frontal Fibrosing Alopecia and Lichen Planopilaris: A Systematic Review
No effective treatment for frontal fibrosing alopecia was found, but oral 5-alpha-reductase inhibitors had the best response; for lichen planopilaris, topical corticosteroids were commonly used but had a high relapse rate.
research Is Androgenetic Alopecia a Photoaggravated Dermatosis?
Sunlight worsens hair loss; protect scalp.
research What Is Alopecia?
Alopecia is a condition causing hair loss that can impact looks and mental health.
research Immune Privilege and Alopecia Areata
Restoring immune privilege in hair follicles could help treat certain types of hair loss.
research Single-Cell Transcriptomics Reveals a Senescence-Associated IL-6/CCR6 Axis Driving Radiodermatitis
Blocking certain immune signals can reduce skin damage from radiation therapy.
research Transfollicular Drug Delivery: Current Perspectives
Transfollicular drug delivery is promising but needs more research to improve and understand it better.
research Management of Primary Cicatricial Alopecias: Options for Treatment
There are many treatments for permanent hair loss disorders, but their effectiveness varies and there's no clear best option.
research Dermocosmetic Aspects of Hair and Scalp
New hair products are being developed to keep hair and scalp healthy for everyone.
research Brain And Muscle Arnt-Like Protein-1 (BMAL1) Controls Circadian Cell Proliferation And Susceptibility To UVB-Induced DNA Damage In The Epidermis
BMAL1 controls skin cell growth and UV damage risk, peaking at night.
research Topical Application of Newly Developed Pseudoceramide Improved Both Skin and Hair Barrier Functions
Applying pseudoceramide improved skin and hair health.
research Baldness May Be Caused by the Weight of the Scalp: Gravity as a Proposed Mechanism for Hair Loss
Baldness might be caused by scalp weight pressing on hair follicles.
research Morpho-Regulation in Diverse Chicken Feather Formation: Integrating Branching Modules and Sex Hormone-Dependent Morpho-Regulatory Modules
Sex hormones, especially estradiol, can change chicken feather shapes and colors.
research Female-Patterned Alopecia in Teenage Brothers with Unusual Histologic Features
Two teenage brothers had a rare, treatment-resistant form of female-pattern hair loss with unusual scalp changes.
research Keratinocytes of the Upper Epidermis and Isthmus of Hair Follicles Express Hemoglobin mRNA and Protein
Skin cells and certain hair follicle areas produce hemoglobin, which may help protect against oxidative stress like UV damage.
research Aberrant Wnt Signaling Induces Comedo-Like Changes in the Upper Hair Follicle
Abnormal Wnt signaling in hair follicle stem cells can lead to acne-like cysts.
research Aberrant Wnt Signaling Induces Comedo-Like Changes in the Murine Upper Hair Follicle
Overactive Wnt signaling in mouse skin stem cells causes acne-like cysts and shrinking oil glands, which some treatments can partially fix.
research Hair Follicle Epidermal Stem Cells Define a Niche for Tactile Sensation
Skin stem cells in hair follicles are important for touch sensation.
research Discovery of Hair-Follicle-Associated Pluripotent Stem Cells
HAP stem cells in hair follicles could help repair nerves and spinal cords.
research Histogenesis of Keratoacanthoma: Histochemical and Immunohistochemical Study
Keratoacanthoma comes from hair follicle cells.
research Decision Letter: Hair Follicle Epidermal Stem Cells Define a Niche for Tactile Sensation
Hair follicle stem cells are crucial for touch sensation and proper nerve structure in mice.
research Live-Imaging the Interface Between Homeostasis and Cancer Initiation
Mutant cells in hair follicles are influenced by their location and interactions with surrounding cells.
research The Epithelial Stem Cell Niche in Skin
Skin's epithelial stem cells are crucial for repair and maintenance, and understanding them could improve treatments for skin problems.
research In Vitro Mesenchymal–Epithelial Interaction Facilitates De Novo Hair Follicle Formation
Adult skin cells can be used to create new hair in a lab.
research Multi-Tasking Epidermal Stem Cells: Beyond Epidermal Maintenance
Epidermal stem cells have various roles in skin beyond just maintenance, including forming specialized structures and aiding in skin repair and regeneration.