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11 citations,
January 2018 in “Acta dermato-venereologica” Researchers found specific genes in the part of hair follicles that could help treat hair disorders.
208 citations,
December 2003 in “Journal of Investigative Dermatology” Certain cells from hair follicles can create new hair and contribute to hair growth when implanted in mice.
January 2022 in “Stem cell biology and regenerative medicine” Dermal sheath cells can help grow new hair follicles and show promise in treating hair loss.
92 citations,
June 2005 in “Journal of Investigative Dermatology” All-trans retinoic acid causes hair loss by increasing TGF-β2 in hair follicle cells.
Different types of sun exposure damage skin cells and immune cells, with chronic exposure leading to more severe and lasting damage.
September 2017 in “Springer eBooks” Stem cells show promise for hair loss treatment, but no effective product for hair regeneration has been developed yet.
6 citations,
February 2014 in “Experimental Dermatology” Hair follicle regeneration is possible but challenging, especially in humans, due to the need for specific cells and a better understanding of how they signal growth.
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January 2001 in “Cell” Adult mouse skin contains stem cells that can create new hair, skin, and oil glands.
1 citations,
April 2022 in “Regenerative Therapy” Activating the GDNF-GFRα1-RET signaling pathway could potentially promote skin and limb regeneration in humans and could be used to treat hair loss and promote wound healing.
207 citations,
March 2012 in “Development” Skin needs dermal β-catenin activity for hair growth and skin cell multiplication.
11 citations,
October 2001 in “Tissue engineering” Cultured epithelium can form hair follicles when combined with dermal papillae.
8 citations,
October 2018 in “Applied sciences” Alginate spheres help maintain hair growth potential in human cells for hair loss treatment.
1 citations,
January 2018 in “Elsevier eBooks” The skin's dermal layer contains true stem cells with diverse functions and interactions that need more research to fully understand.
January 2019 in “Advances in stem cells and their niches” Skin health and repair depend on the signals between skin stem cells and their surrounding cells.
115 citations,
December 2017 in “Wiley Interdisciplinary Reviews-Developmental Biology” Skin cells called dermal fibroblasts are important for skin growth, hair growth, and wound healing.
44 citations,
December 1991 in “Annals of the New York Academy of Sciences” EGF and FGF help hair growth by affecting cell differentiation and fiber growth.
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August 2020 in “Cell stem cell” Dermal fibroblasts have adjustable roles in wound healing, with specific cells promoting regeneration or scar formation.
106 citations,
October 2016 in “Cell Stem Cell” PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.
41 citations,
September 2010 in “Journal of dermatological science” Bone marrow and umbilical cord stem cells can help grow new hair.
299 citations,
January 2018 in “Journal of Clinical Investigation” Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.
December 2023 in “Animals” The study mapped yak skin cells to understand hair growth better.
November 2015 in “Hair transplant forum international” Early attempts at using cloned cells for hair transplants failed, but 3D cell growth showed some promise.
65 citations,
November 2012 in “Tissue Engineering Part B-reviews” Hair follicle stem cells are a promising source for tissue repair and treating skin or hair diseases.
54 citations,
June 2003 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Disruptions in hair follicle fibroblast dynamics can cause hair growth problems.
43 citations,
August 2008 in “Regenerative Medicine” Scientists created early-stage hairs from mouse cells that grew into normal, pigmented hair when implanted into other mice.
47 citations,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” Premature graying of hair may suggest health issues and currently lacks effective treatments.
19 citations,
November 2001 in “Journal of Investigative Dermatology Symposium Proceedings” Human hair follicles can regenerate and recover after severe injury by going through a brief abnormal resting phase before growing again.
February 2024 in “Frontiers in physiology” Modifying certain signals in the body can help wounds heal without scars and regrow hair.
211 citations,
February 2009 in “European journal of pharmaceutics and biopharmaceutics” Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.