Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

Nephronectin helps attach muscle cells to hair follicles.

This study reports that sebaceous glands can regenerate after injury through stem cell plasticity, with hair-follicle-derived stem cells replacing sebaceous gland progenitors and playing a crucial role in the regeneration process, which is dependent on FGFR2 signaling and aided by hair growth induction.

This study found that CD34- melanocyte stem cells regenerated pigmentation more efficiently, while CD34+ cells showed potential for neuron myelination, suggesting different therapeutic applications for each population.

In this study, researchers found that mouse hair follicles recruit Langerhans cells by secreting chemokines, acting as key portals for these cells in both mice and humans.

This study identified a novel MTS24-positive murine keratinocyte population with increased colony-forming ability, suggesting these cells may serve as a new reservoir of proliferative progenitor or stem cells in hair follicles.

This study found that the phenotype of Hedgehog/Gli-driven skin tumors in mice depends on the cell of origin, tissue context, and level of oncogenic signaling.

Stem cells in developing hair follicles move to specific areas as they mature.

This study found that mutations in the hairless gene in mice disrupt hair follicle integrity during catagen, leading to baldness due to disintegrating epithelial structures and loss of normal dermal papilla.

This study found that nestin-expressing cells in the hair follicle bulge exhibit multipotent stem cell-like properties and can generate neural cells both in vitro and in vivo.

This article reviews key questions in skin biology, particularly the mechanisms of hair follicle patterning and the role of stem cells in the epidermis, reporting no new results.

In this study, researchers found that Notch signaling is crucial for late-stage epidermal differentiation and postnatal hair cycle homeostasis by regulating hair follicle stem cell proliferation and differentiation.

This study found that human hair follicle stem cells formed more colonies and adhered more rapidly, while transit-amplifying cells showed significantly greater mobility.

Keratin patterns in hair follicles help understand hair growth and potential hair and nail disorders.

This study observed that epidermal-specific deletion of aPKCλ in mice disrupts hair follicle stem cell quiescence, leading to altered hair follicle cycling and skin anomalies.

This study found that MED1 plays a role in maintaining keratinocyte quiescence and hair follicle stem cell populations, as its absence in mice led to increased keratinocyte proliferation and reduced stem cell numbers.

In this study, researchers found that Sox9 is critical for determining whether Nestin⁺ stem cells in adult mouse skin develop into melanocytes or glial cells, offering insights into possible paths for melanoma research.

In this study, researchers found that the matriptase-HGF-c-MET pathway may be activated in proliferative cells of human hair follicles and sebaceous glands, suggesting a potential role in hair growth regulation.

This review examines the complex mechanisms that regulate skin stem cell development, activation, and differentiation, emphasizing the molecular signaling pathways that influence their fate and contribute to skin homeostasis.

This study found that the alcohol extract of Vernonia anthelmintica may counteract stress-induced hair follicle growth inhibition in mice, potentially offering a new approach for treating stress-related hair loss.

This study found that altering cyclin-dependent kinase 4 (CDK4) levels in the bulge region of hair follicles affects the balance of stem cell numbers, potentially influencing hair follicle self-renewal and proliferation.

In this study, azelaic acid was found to enhance UVB protection in bulge cells and, when combined with minoxidil, may promote hair growth through increased Sonic hedgehog protein expression in hair follicles.

This study identifies a specific cell population, PDGFRα+/Sca1+/CD34+ mesenchymal cells, which play a crucial role in regenerating hair follicles by promoting the downgrowth phase of the hair cycle, offering insights into organ morphogenesis and stem cell niches essential for adult hair regeneration.

Specific immune cells and pathways contribute to hair follicle inflammation and hair loss, suggesting potential treatments for lichen planopilaris.

In this ex vivo and in vitro study, researchers found that capacitive resistive electrical transfer therapy increased cell proliferation and reduced cell death in hair follicles from patients with androgenic alopecia, suggesting potential benefits for alopecia treatment.

This study observed that using a relaxed suture technique on scalp incisions may prevent linear scars by reducing pressure on upper stem cells.

This study found that polymeric micelle nanocarriers delivered pharmacologically relevant amounts of spironolactone to the epidermis and upper dermis, with higher delivery to pilosebaceous units, suggesting potential for treating glucocorticoid-induced impaired wound healing and pilosebaceous androgen-related skin diseases.

In this study, nestin-expressing cells in the hair follicle bulge, marked by GFP in transgenic mice, were identified as progenitors of the hair follicle outer-root sheath.

This study suggests that keratin expression in keratoacanthomas resembles that in the upper part of hair follicles, implying a potential origin, but it is indistinguishable from squamous cell carcinomas in terms of keratin reactivity.

Activating the Eda/Edar pathway improves wound healing by enhancing hair follicle growth.

This study found that horizontally bisected donor hairs can be used to create finer hairlines, with about 46-47% growth reported in transplanted hair shafts and bulbs.