research Alcohol and Prostate Cancer: Time to Draw Conclusions
Drinking a lot of alcohol increases the risk of prostate cancer and can worsen the condition.
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90-120 / 1000+ results research Moxibustion Improves Ovarian Function Based on the Regulation of the Androgen Balance
Moxibustion may help improve ovarian function by changing androgen levels.
research Androgens and Androgen Receptor in the Management of Skin Diseases
Understanding how androgens and their receptors work can lead to improved treatments for skin diseases.
research Design of Liposome Formulations for CRISPR/Cas9 Enzyme Immobilization: Evaluation of 5-Alpha-Reductase Enzyme Knockout for Androgenic Disorders
New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.
research Application of Stem Cells in Regenerative Medicine
Stem cells and their exosomes show promise for repairing tissues and healing wounds when delivered effectively, but more research is needed on their tracking and optimal use.
research Regulation and Role of GLI1 in Cutaneous Squamous Cell Carcinoma Pathogenesis
GLI1 might protect against the start of skin cancer and is not linked to cancer severity.
research Human Fibroblast-Derived Matrix Hydrogel Accelerates Regenerative Wound Remodeling Through Interactions With Macrophages
A new hydrogel made from human cells improves wound healing by working with immune cells to promote repair.
research Concept of Tinea Capitis
Terbinafine is the most effective treatment for tinea capitis, a scalp infection often confused with other conditions.
research Anal Involvement in Pemphigus Vulgaris: Study on Recurrence and Treatment Outcomes
Most patients with anal Pemphigus Vulgaris had repeated episodes but fully recovered with treatment, without long-term problems.
research Hormonal Therapy for Acne
Hormonal treatments, including birth control and antiandrogens, can effectively treat acne in women.
research 5α-Reductase Activity in the Prostate
Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.
research Systemic Lupus Erythematosus: Definitions, Contexts, Conflicts, Enigmas
The document concludes that anti-dsDNA antibodies are not unique to SLE and their use as indicators is doubtful, highlighting the need for better understanding and classification of the disease.
research Retinoid-Mediated Stimulation of Steroid Sulfatase Activity in Myeloid Leukemic Cell Lines Requires RARα and RXR and Involves the Phosphoinositide 3-Kinase and ERK-MAP Kinase Pathways
Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.
research Establishment of a Culture Model for the Prolonged Maintenance of Chicken Feather Follicles Structure In Vitro
Scientists have developed a method to keep chicken feather follicles alive and structurally intact in a lab for up to a week.
research Stimulation of Hair Regrowth in an Animal Model of Androgenic Alopecia Using 2-Deoxy-D-Ribose
2-deoxy-D-ribose gel may help regrow hair in cases of hair loss.
research Overexpression of Aldo-Keto Reductase 1C3 in LNCaP Cells Diverts Androgen Metabolism Towards Testosterone Resulting in Resistance to the 5α-Reductase Inhibitor Finasteride
Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.
research Evaluation of Hair Loss
Detailed patient history and physical exams are crucial for diagnosing hair loss.
research Antiandrogen Therapy for Skin and Hair Disease
Antiandrogen therapies are beneficial for treating skin and hair conditions related to androgen levels.
research Hirsuties
Hirsutism in women is often due to hormone sensitivity and has significant psychological effects.
research Biotin
Biotin supplements are unnecessary for most people but may help with certain conditions like biotin deficiency, brittle nails, and some hair loss.
research Immunological And Some Biological Biomarkers Investigation In Patients With Systemic Lupus Erythematosus
No single biomarker is reliable enough for diagnosing and assessing SLE.
research Predictive Modeling of Patient Response to JAK/STAT Inhibitors and Dynamic Patient-Matching
Machine learning can predict how well patients with alopecia areata will respond to certain treatments.
research Is Dehydroepiandrosterone a Hormone?
Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.
research Alopecia Areata Update
Half of people with Alopecia Areata may see hair regrowth within a year without treatment, but recovery is unpredictable.
research The 5 Alpha-Reductase Isozyme Family: A Review of Basic Biology and Their Role in Human Diseases
The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.
research Flares of Systemic Lupus Erythematosus During Pregnancy and the Puerperium: Prevention, Diagnosis, and Management
Pregnancy can increase lupus activity, but careful planning and treatment can improve outcomes.
research Transient Mitochondrial DNA Double Strand Breaks in Mice Cause Accelerated Aging Phenotypes in a ROS-Dependent but p53/p21-Independent Manner
Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.
research Antiandrogen Therapy in Dermatology
Antiandrogens can help treat skin conditions like acne and excessive hair in women when used carefully.
research Hormonal Therapies for Acne
Hormonal treatments can improve acne, but they come with potential side effects and risks.
research Comparative Transcriptomic Analysis of Dermal Wound Healing Reveals De Novo Skeletal Muscle Regeneration in Acomys Cahirinus
The African spiny mouse can fully regenerate its muscle without scarring, unlike the common house mouse.