192 citations
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April 2019 in “ACS nano” In a mouse model, this study demonstrated that a microneedle patch system using keratin and integrated with MSC-derived exosomes and UK5099 promoted hair regrowth more efficiently than traditional delivery methods.
78 citations
,
September 2008 in “International Journal of Cosmetic Science” This review outlines various clinical methods for assessing ageing skin and discusses their application in supporting the efficacy claims of anti-ageing treatments, but it reports no new clinical results.
45 citations
,
October 2014 in “Stem cell research & therapy” This study found that using 3D Gel-C6S-HA scaffolds seeded with VEGF165-modified rat hair follicle stem cells enhanced angiogenesis and vascularization in tissue-engineered skin, improving wound healing.
43 citations
,
July 1984 in “Clinical and Experimental Dermatology” This study found that women with common baldness treated with cyclical antiandrogen therapy for 52 weeks experienced increased hair density and a higher percentage of hairs in the anagen growth phase.
39 citations
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November 2017 in “Journal of The American Academy of Dermatology” This review presents standardized methods for assessing and tracking hair loss in alopecia areata but reports no clinical results, with the authors noting time limitations in clinical practice.
33 citations
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May 2013 in “Andrologia” This study identified several herbs, including Ganoderma lucidum and Urtica dioica, that showed promising 5α-reductase inhibitory activity suggesting potential use in managing androgenic disorders.
33 citations
,
January 1991 in “The Journal of Dermatologic Surgery and Oncology” This article describes incisional slit grafting as an improved hair transplantation method, using smaller grafts and conserving vascular supply to enhance graft yield and achieve a more natural hairline, but reports no new research results.
25 citations
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May 2020 in “Aesthetic Surgery Journal” In this systematic review, tSVF-based therapy demonstrated favorable outcomes for various pathologies, including aged skin and osteoarthritis, with low incidence of adverse events, while highlighting the need for further research into optimal protocols and mechanisms of action.
25 citations
,
December 2017 in “The Journal of Clinical Endocrinology & Metabolism” This study found that using an oral contraceptive with bicalutamide significantly reduced hirsutism in women with PCOS compared to an oral contraceptive alone, although it increased total cholesterol and LDL levels.
25 citations
,
June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” This study found that among Japanese women with diffuse hair loss, decreased hair density without changes in vellus hair was the most common and distinct pattern observed, highlighting differences from previous observations in other populations.
23 citations
,
September 2020 in “Journal of Cosmetic Dermatology” This review discusses the potential applications of injectable platelet‐rich fibrin in various conditions and reports no new clinical results; the authors highlight its favorable use in comparison to existing treatments.
23 citations
,
June 2018 in “Facial Plastic Surgery” This review suggests that platelet-rich plasma is a low-risk treatment for androgenic alopecia with good patient satisfaction and positive objective outcomes, but further research is needed to refine methods and standardize outcome measurements.
22 citations
,
January 2014 in “Biological & Pharmaceutical Bulletin” This study found that ginsenoside F2 may suppress hair cell apoptosis and improve hair growth outcomes in a DHT-induced hair loss model more effectively than finasteride.
21 citations
,
January 2010 in “International Journal of Trichology” This study concluded that TrichoScan is error-prone in its current form and overestimates certain hair growth parameters, with results not aligning with clinical severity of alopecia.
18 citations
,
November 2016 in “Journal of Oral and Maxillofacial Surgery” This review discusses platelet-rich plasma for androgenic alopecia and reports beneficial effects on hair density and quality, but suggests more rigorous studies are needed for conclusive evidence.
17 citations
,
June 2011 in “The journal of investigative dermatology/Journal of investigative dermatology” This study observed that mice with a Cx43 mutation exhibited slower and asynchronous hair regrowth with severe cuticle weathering, mimicking aspects of hair phenotype in some ODDD patients.
17 citations
,
October 2002 in “Dermatologic Surgery” This article provides a guide for surgeons on repairing poorly executed hair transplants, emphasizing meticulous techniques and optimal use of limited hair supply to achieve cosmetic improvements.
14 citations
,
June 2021 in “British journal of dermatology/British journal of dermatology, Supplement” This paper presents consensus guidelines for standardized diagnostic criteria and assessment methods for frontal fibrosing alopecia to improve clinical research and data collection globally.
11 citations
,
December 2016 in “Frontiers in Psychology” In this study, researchers used computer-generated models to demonstrate that subtle changes in hair diameter, density, and style significantly affect perceptions of age, health, and attractiveness.
11 citations
,
July 2008 in “Facial Plastic Surgery Clinics of North America” This article discusses the benefits of follicular unit transplantation for male hair restoration, highlighting its ability to achieve natural-looking results with minimal recovery time and low risk of complications, and reports no new clinical results.
7 citations
,
October 2018 in “Journal of Craniofacial Surgery” In this study, researchers observed the patterns of hair distribution and scalp anatomy in Chinese young adult males, finding significant variations in hairline shape, hair density, and follicular unit structure.
6 citations
,
May 2021 in “Aesthetic Surgery Journal” This study found that intradermal injections of platelet-rich plasma were equally safe and effective for treating androgenetic alopecia, with higher platelet numbers possibly enhancing hair density and follicle diameter.
4 citations
,
August 2018 in “Facial Plastic Surgery Clinics of North America” This review discusses the use of platelet-rich plasma in treating androgenetic alopecia and alopecia areata, observing overall positive clinical responses without identifiable complications, and reports no new clinical results.
3 citations
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February 2021 in “Medical journal, Armed Forces India” In this observational study, the combination of PRP and 5% minoxidil was more effective than minoxidil alone in promoting hair growth in men with androgenetic alopecia.
July 2026 in “Lasers in Medical Science” In this study, the Peninsula Timerevert Needle was found to provide effective treatment for skin photoaging and acne scars with less pain and shorter treatment duration compared to EndyMed, although it caused more bleeding.
July 2026 in “Innovations in Pharmaceutical Sciences & Care” In this case report, a 31-year-old man with frontal hairline recession saw a marked improvement in hair density and scalp appearance after undergoing six mesotherapy sessions alongside twice-daily application of 5% minoxidil, attributed to the treatment protocol combining nutrients, bioactives, and topical minoxidil.
In this study, Neeli Bhringadi hair oil showed statistically significant improvements in hair growth rate, density, thickness, and reduction in premature graying on participants with androgenetic alopecia and hair graying over 120 days, supporting its potential use in integrative hair care.
July 2026 in “Clinical Cosmetic and Investigational Dermatology” In this study, a liposomal-encapsulated Sesbania grandiflora formulation significantly improved hair and scalp health in adults with hair loss over 180 days, showing enhanced hair density, thickness, growth rate, and tensile strength compared to placebo, with no related adverse events reported.
January 2026 in “Forum Dermatologicum” This review concluded that LED-based photobiomodulation is generally safe and effective for certain dermatologic conditions, though consumer devices often show less efficacy compared to professional systems.
In this study, a Monte Carlo-generated synthetic cohort analysis found that higher simulated cannabis exposure was linked to increased self-assessed hair loss severity and reduced follicular density, suggesting potential connections worth exploring in further clinical research.