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The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

Patients with both connective tissue disease and acid reflux are more likely to have certain symptoms and physical signs.

BLIMP1 is essential for skin maintenance but not for defining sebaceous gland progenitors.

Smad1 and Smad5 are essential for hair follicle development and stem cell sleepiness.

VEGFR-2 is active in hair follicles, sebaceous glands, sweat glands, and skin on the human scalp.

Activating a protein called β-catenin in adult skin can make it behave like young skin, potentially helping with skin aging and hair loss.

Grafted rodent and human cells can regenerate hair follicles, but efficiency decreases with age.

Compartmentalized organization might be crucial for stem cells to effectively respond to growth or injury.

Ovol2 is crucial for hair growth and skin healing by controlling cell movement and growth.

Stem cell therapies show promise for treating various diseases but face challenges in clinical use and require better monitoring techniques.

Certain mature cells in mouse lungs can turn back into stem cells to aid in tissue repair.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

Keratin genes change gradually during skin cell development and should be used carefully as biomarkers.

Sebaceous glands can heal and regenerate after injury using their own stem cells and help from hair follicle cells.

Obesity can weaken the skin's ability to fight infections because fat cells stop and reduce the infection-fighting properties of nearby stem cells.

Epithelial-mesenchymal interactions control hair growth cycles through specific molecular signals.

Melanocyte stem cells in hair follicles are key for hair color and could help treat greying and pigment disorders.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

Keratin fibrils in hair form and stop growing at specific points in the follicle.

CIP/KIP proteins help stop cell division and support hair growth.

Epidermal stem cells have various roles in skin beyond just maintenance, including forming specialized structures and aiding in skin repair and regeneration.

Androgens affect bone and fat cell development differently based on the cells' embryonic origin.

Keratin gene expression helps understand different types of skin cells and their development, and should be used carefully as biological markers.

Dental pulp stem cells might not reliably become neurons.

The document concludes that stem cells and their environments are crucial for skin and hair health and have potential for medical treatments.

The model shows that factors like follicle shape and stiffness are key for hair growth and anchoring.

Human stem cells can help form hair follicles in mice.

Low oxygen areas help maintain and protect blood stem cells by using a simple sugar breakdown process for energy and managing their activity levels.

Auto-antibody testing is a useful but not definitive tool in diagnosing interstitial lung diseases, and using a specific algorithm could make testing more cost-effective.