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The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.

Chemotherapy in the first trimester of pregnancy is risky, but in the second and third trimesters, it's generally safe with careful drug selection and timing.

Stress can worsen skin and hair conditions by affecting the skin's immune response and hormone levels.

Stem cell-derived conditioned medium shows promise for treating various medical conditions but requires standardized production and further validation.

The article suggests managing interferon beta therapy side effects in MS with dose adjustments, medications, and patient education.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Erectile dysfunction is increasingly common in men under 40, with many physical and psychological causes, and various treatment options available.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

Blood vessels and specific genes help turn cartilage into bone when bones heal.

Transplant success has improved with better immunosuppressive drugs and donor matching.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

MicroRNA-302 helps improve the conversion of body cells into stem cells by blocking NR2F2.

Pregnancy can cause skin pigmentation, stretch marks, and changes in hair, nails, and sweat glands, with most resolving after birth.

The document concludes that specific itchy skin diseases during pregnancy have varying fetal risks and treatments, including corticosteroids and other medications.

Pregnancy can increase lupus activity, but careful planning and treatment can improve outcomes.

Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.

Created material boosts hair growth and kills bacteria for wound healing.

The circadian clock influences the behavior and regeneration of stem cells in the body.

Most dermatologic medications are safe during pregnancy and breastfeeding, but some should be avoided due to potential risks.

European guidelines recommend regular eye and ear exams, skin care, vitamin D supplements, and cautious use of medications for managing congenital ichthyoses.

Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.

Testosterone may slow down wound healing and increase inflammation.

Patients with Bohring-Opitz syndrome and ASXL1 mutations need regular kidney ultrasounds to check for tumors.

Mothers and newborns with dental fillings had higher mercury in their hair, but getting fillings during pregnancy didn't raise mercury levels further.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Vitiligo is not linked to coeliac disease, but a small number of alopecia areata patients may have it, suggesting they should be tested for coeliac disease.

Stem cell therapy may help treat tough hair loss cases.

Minoxidil lowers blood pressure, increases heart rate, and improves blood flow in dogs.