126 citations
,
January 2009 in “International Journal of Trichology” This review discusses the potential role of oxidative stress in hair graying and age-related alopecia, emphasizing the need for new strategies to counteract these effects, but reports no new results.
89 citations
,
June 2012 in “Anais Brasileiros de Dermatologia” This review compiles epidemiological data on actinic keratoses and suggests promoting strategies like early diagnosis and photoprotection to prevent progression to skin cancer, but it reports no new clinical findings.
80 citations
,
January 1979 in “Journal of Surgical Oncology” This paper reviews keratoacanthoma as a tumor that resembles but rarely progresses to squamous cell carcinoma, detailing its stages, potential origins, and distinguishing features from other similar growths, without reporting new clinical results.
77 citations
,
December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that human skin expresses proenkephalin, whose expression is upregulated by environmental stress and varies in pathological conditions, increasing in psoriasis and decreasing in melanocytic tumors.
76 citations
,
October 2011 in “Clinica Chimica Acta” In this study, ultraviolet irradiation and immersion in shampoo and hot water significantly reduced hair cortisol, illustrating a two-stage process of cortisol loss that may impact chronic stress assessment.
75 citations
,
August 2005 in “Expert Opinion on Pharmacotherapy” This review discusses the use of acitretin, a retinoid approved since 1997, for various forms of psoriasis and its potential benefits in combination therapy, but reports no new clinical findings.
74 citations
,
September 2003 in “The Journal of Immunology” This study found that PKCα activation in transgenic mice induces keratinocyte apoptosis and mediates neutrophilic skin inflammation via different pathways, suggesting potential mechanisms for cutaneous inflammatory diseases.
69 citations
,
January 1995 in “PubMed” This study suggests that the structure and function of mouse melanocytes in the epidermis and hair bulb are influenced by genetic factors and local tissue environment, including hormones and growth factors.
65 citations
,
November 2008 in “Pediatric Dermatology” This study observed that phototherapy is an effective and well-tolerated treatment for childhood dermatoses, particularly for psoriasis and pityriasis lichenoides chronica.
63 citations
,
April 1985 in “Journal of the American Academy of Dermatology” This study observed that topical PUVA treatment led to excellent or good hair regrowth in 45.4% of patients with alopecia areata, though many experienced relapse after treatment stopped.
62 citations
,
January 2003 in “Dermatology” This review suggests that androgenetic alopecia may be exacerbated by exposure to ultraviolet radiation and proposes considering it as a photoaggravated condition requiring photoprotection.
60 citations
,
June 1997 in “Journal of The American Academy of Dermatology” This review discusses the basic biology of apoptosis and its relevance to skin diseases, without presenting new research findings.
45 citations
,
September 2012 in “The Journal of Steroid Biochemistry and Molecular Biology” This study found that deleting β-catenin in epidermis-specific VDR knockout mice did not prevent UVB-induced skin tumors, indicating β-catenin does not compensate for VDR's role in tumor suppression.
41 citations
,
August 1988 in “Journal of The American Academy of Dermatology” In this case report, a patient with subacute cutaneous lupus erythematosus and exfoliative erythroderma achieved complete remission with systemic corticosteroids and long-term hydroxychloroquine.
39 citations
,
March 2017 in “Dermatologic clinics” This article reviews the process of repigmentation in vitiligo and emphasizes the role of UV light as the most potent stimulus, with no new clinical findings reported.
32 citations
,
September 1989 in “Medical Clinics of North America” This review describes the types of skin lesions associated with systemic lupus erythematosus, discussing their histopathological features, serologic associations, pathogenesis, and prognostic implications.
31 citations
,
February 1999 in “Dermatologic surgery” This report describes a case where solar-induced postinflammatory hyperpigmentation following laser hair removal was treated with a combination of topical treatments and serial TCA peels, resulting in only slight improvement.
24 citations
,
March 2015 in “Best Practice & Research in Clinical Obstetrics & Gynaecology” This review discusses physiological skin changes and specific dermatoses in pregnancy but reports no new clinical results, emphasizing careful diagnosis and management due to potential fetal risks in rare cases.
24 citations
,
January 2009 in “International Journal of Trichology” This review discusses the mechanisms by which sunlight exposure aggravates hair aging and highlights the role of hair pigments in providing photochemical protection, reporting no new results.
17 citations
,
May 2018 in “Journal of Biomedical Optics” This review discusses how the optical properties of human hair might contribute to melanoma development but reports no new experimental findings, suggesting further research is needed to support this hypothesis.
17 citations
,
March 2016 in “PubMed” This review discusses the potential and limitations of adipose-derived stem cells and their conditioned medium for hair regeneration, highlighting novel preconditioning methods to enhance their effectiveness, without presenting new clinical results.
17 citations
,
October 2009 in “Dermatology” This study reported that ultraviolet light treatment from a Kromayer lamp stimulated hair growth in four out of six patients with alopecia, whereas intralesional triamcinolone acetonide had a mixed effect.
15 citations
,
December 2016 in “Obstetrics & Gynecology” This review discusses the effects of pregnancy on melanocytic nevi and reports no new clinical results; it suggests that changing nevi during pregnancy should be evaluated similarly to those in nonpregnant patients.
14 citations
,
July 2022 in “Nutrients” This review discusses new research on the role of retinoids in skin and hair health and reports no clinical results.
14 citations
,
October 2021 in “Dermatology and Therapy” This study found that photoexposure significantly increased the gene expression of altered elastin, MMP12, and LOX, as well as the protein expression of tropoelastin and fibrillin-1, in skin models.
14 citations
,
September 2017 in “Clinical and Experimental Dermatology” In this report, a 26-year-old man with folliculitis decalvans unresponsive to standard treatments experienced significant disease clearance after 25 months of systemic photodynamic therapy, marking the first documented use of this therapy for this condition.
14 citations
,
September 2016 in “Journal of Photochemistry and Photobiology B Biology” This study observed that mercury-lamp irradiation may cause cleavage of disulfide bonds in keratins of white hair, leading to the formation of thiols in laboratory settings.
13 citations
,
February 1999 in “International Journal of Cosmetic Science” This study observed a higher incidence of telogen effluvium from July to October, suggesting a summer-related effect in populations above the Tropic of Cancer, possibly influenced by ultraviolet light.
11 citations
,
October 2022 in “Clinical Cosmetic and Investigational Dermatology” In this study, SNPs in genes affecting skin pigmentation were linked to each skin type's unique response to environmental stress, suggesting potential for personalized skin care products.
11 citations
,
April 2013 in “SpringerPlus” This study reports that melanocytes form a defined photoresponsive network in the skin that reads environmental light cycles and may influence the sleep-waking cycle similar to the pineal gland.