21 citations
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March 2021 in “Molecules” This study found that a new quercetin-loaded self-nanoemulsifying drug delivery system improved quercetin bioavailability by 149.8% compared to its suspension in rats.
2 citations
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May 2022 in “Diagnostics” This study confirmed that 25(OH)D3 can be detected in hair samples from healthy young adults, but no correlation was found between hair and serum 25(OH)D3 concentrations, indicating limited potential as a standalone biomarker.
October 2025 in “Phytomedicine” This study demonstrates that Bazi Bushen capsules may have therapeutic potential against skin photoaging in mice by enhancing NRF2 expression and targeting the KEAP1-NRF2 pathway.
34 citations
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January 2016 in “Analytical Chemistry” This study reports that a new DART-HRMS method can effectively analyze intact hair for drug use timelines, with cocaine detection aligning with forensic standards and identifying multiple drugs from high-resolution data.
26 citations
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August 2021 in “Medicine” This study found that low levels of SHBG and testosterone were associated with higher mortality in men with severe COVID-19.
4 citations
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May 2024 in “Rapid Communications in Mass Spectrometry” This study demonstrated that GP derivatization improves mass spectral analysis of spironolactone and its metabolites by reducing in-source fragmentation and enhancing signal clarity, laying the groundwork for future advancements in reaction optimization and quantitative assay development.
November 2025 in “Animals” In this study, hair samples from dogs with chronic degenerative valve disease showed significantly higher concentrations of certain endocrine-disrupting chemicals compared to healthy dogs, suggesting a potential link that warrants further investigation.
August 2025 in “Frontiers in Pharmacology” In this study, PA-011, a traditional Chinese medicine extract, was shown to improve hair growth in alopecia areata model mice by reducing skin inflammation and altering skin microbiota, indicating its potential therapeutic role for this condition.
December 2023 in “Frontiers in Medicine” In this study, the researchers found that measuring tacrolimus levels in scalp hair could be a reliable method for monitoring drug exposure in kidney transplant recipients, offering an alternative to frequent blood tests by utilizing self-collected hair samples.
November 2023 in “South African journal of botany” This study found that Eclipta alba (L.) cultivated in France exhibited significant anti-inflammatory, antioxidant, and anti-collagenase activities, attributed mainly to compounds like wedelolactone and demethylwedelolactone, suggesting potential use as an anti-aging cosmetic ingredient.
54 citations
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June 2020 in “Pharmaceutics” This review discusses the advancements in using "soft" colloidal nanocarriers for delivering photosensitive agents and highlights their potential applications in treating diseases like cancer, but it reports no new clinical results.
September 2025 in “International Journal of Molecular Sciences” In this review, researchers explored hair as a promising tool for identifying biomarkers in schizophrenia, highlighting its potential for supporting personalized medicine through ease of sampling, though acknowledging challenges like individual variability and methodological inconsistencies.
August 2025 in “Current Issues in Molecular Biology” This study demonstrated that Periplaneta americana extract significantly promoted hair regeneration in depilated mice by enhancing superoxide dismutase activity, upregulating vascular endothelial growth factor, modulating the FOXO/PI3K/AKT pathway, and restoring skin microbiome balance, suggesting its potential as a novel therapeutic candidate for alopecia.
May 2023 in “Scientific Reports” This study found that Lepidium sativum seed extract showed potential in treating alopecia in rats by reducing 5(alpha)-dihydrotestosterone levels and improving hair length compared to minoxidil.
188 citations
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December 2020 in “Foods” This review explores the potential health benefits of food bioactive compounds, specifically polyphenols, as preventive agents against non-communicable diseases like cancer and cardiovascular disorders, while also addressing challenges like bioavailability and industrial applications.
41 citations
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June 2023 in “Antioxidants” This review highlights that pomegranate exhibits promising beneficial effects in preclinical and clinical studies for cardiovascular and non-cardiovascular diseases, though further research is needed on its bioavailability and metabolites for effective therapeutic use.
9 citations
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July 2025 in “Pharmaceuticals” This review highlights the therapeutic potential of plant-derived exosomes, noting their larger size compared to animal-derived exosomes and usefulness in targeted drug delivery and inter-kingdom communication. It summarizes existing research on their biogenesis, characterization, and engineering for drug delivery, indicating significant opportunities for biotechnological advancements.
9 citations
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December 2022 in “Phytomedicine” This review discusses the pharmacology, toxicology, and clinical efficacy of flavonoids and saponins, highlighting the need for more data on their pharmacokinetics, interactions, and toxicities as most research is still in vitro.
8 citations
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July 2023 in “Frontiers in Pharmacology” This review highlights cepharanthine as a promising candidate for COVID-19 treatment due to its antiviral activity against SARS-CoV-2 and favorable pharmacokinetic and safety profile, but reports no new clinical results.
1 citations
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September 2023 in “Molecules (Basel. Online)” This source highlights that while plant sterols show potential benefits and applications in various industries, significant research gaps, including their complex structures and mechanisms, hinder their broader use, emphasizing the need for innovative sources and sustainable methods for their study.
1 citations
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May 2022 in “Frontiers in Pharmacology” This study found that astilbin downregulates effector CD4+ T cell activities through the CYP1B1/ROS/PPARγ pathway, suggesting its potential use in treating inflammation.
August 2025 in “Aesthetic Plastic Surgery” This review explores the mechanisms, current products, challenges, and innovative approaches related to cosmetics for hair loss prevention and growth promotion, emphasizing the need for multidisciplinary cooperation to enhance product development and market success.
April 2025 in “Natural Product Communications” This study found that essential oils from A. sinensis and L. sinense 'chuanxiong' were safe and significantly promoted hair regrowth in mice with dehydrotestosterone-induced androgenetic alopecia, outperforming 3% minoxidil in follicle number and dermal thickness improvements, suggesting potential use in hair loss treatments.
April 2023 in “JMIR Research Protocols” In this study, researchers are constructing a comprehensive data set from 997 adult participants in Japan to develop a statistical model that explores the relationships among various health parameters, aiming to enable personalized and preventive health care interventions based on empirical data.
February 2023 in “Frontiers in Pharmacology” This study found that the water extract of Cacumen Platycladi promotes hair growth and follicle development in mice, possibly by influencing dermal papilla cells through the Akt/GSK3β/β-Catenin signaling pathway.
63 citations
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February 2017 in “ACS biomaterials science & engineering” In this study, polydopamine emerged as a safe and effective alternative to traditional hair dyes like PPD for dyeing gray hair permanently, showing resistance to detergents and causing less toxicity and hair loss in mice.
30 citations
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August 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that TGase 3 may contribute to hair fiber scaffolding by forming specific isopeptide bonds between keratin intermediate filaments and keratin-associated proteins.
2 citations
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June 2025 in “MedComm – Biomaterials and Applications” This study reviews the potential of antioxidant plant compounds in improving wound healing for diabetic patients by reducing oxidative stress, controlling bacterial infections, and modulating inflammation, thereby promoting tissue regeneration and addressing key challenges in diabetic wound care.
12 citations
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November 2022 in “Cosmetics” This review discusses 3D printing developments in topical delivery systems, highlighting the potential for 3D printed microneedles to become prominent in personalized cosmetic applications, but reports no new experimental results.
111 citations
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April 2023 in “Ultrasonics Sonochemistry” This review discusses the extraction, purification, and biological activities of maidenhairtree polysaccharides, emphasizing the higher efficiency of ultrasound-assisted extraction, but it reports no new clinical results.