17 citations
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October 1980 in “PubMed” In this study, sodium valproate achieved complete seizure control in 82% of children as monotherapy, with higher plasma levels potentially linked to resistant cases.
16 citations
,
August 2004 in “Tetrahedron” In this study, all stereoisomers of cyoctol were synthesized and tested, revealing that contrary to initial patent claims, cyoctol does not function as an anti-androgen.
15 citations
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November 2020 in “Pharmaceutics” In this ex vivo and mouse model study, Tofacitinib-loaded nanoparticles demonstrated enhanced delivery of the drug into hair follicles and reduced inflammatory effects compared to conventional forms, indicating potential for safer, topical use in treating alopecia areata.
13 citations
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August 2018 in “Journal of Molecular and Cellular Cardiology” This study demonstrated that finasteride treatment reduced cardiac dysfunction and hypertrophic remodeling in mice after myocardial infarction, suggesting potential as a therapeutic strategy for heart failure.
13 citations
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December 2005 in “Dermatologic surgery” In this study, Er:YAG laser therapy initially improved the appearance of eruptive vellus hair cysts but was ultimately ineffective due to early recurrence and concerns about atrophy or scarring.
6 citations
,
April 2013 in “Alternative and Complementary Therapies” Raspberry ketone lacks sufficient human research to support health benefit claims and requires more rigorous studies to confirm its safety and effectiveness.
5 citations
,
May 2019 in “Archives of Dermatological Research” This study reported that narrowband UVB treatment significantly increased WNT7B, WNT10B, and TCF7L2 gene expression in lesional skin of psoriasis patients, suggesting these genes may play a role in psoriasis pathogenesis.
4 citations
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September 2016 in “Journal der Deutschen Dermatologischen Gesellschaft” This study found that 7.9% of dermatological outpatients at a German hospital had clinically relevant body dysmorphic concerns, highlighting the need for psychotherapeutic support due to poor social adaptation and high motivation for change.
4 citations
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August 2014 in “Dermatology and Therapy” This study suggests that LOYON® is safe, well tolerated, and effective in reducing scaling from cradle cap in infants and children without causing spot bleedings.
3 citations
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October 2023 in “Military Medical Research/Military medical research” This review explores the crucial role of regulatory T cells in skin wound healing, emphasizing their involvement in balancing immune responses and promoting regeneration. It also discusses Tregs' operations in fibrosis, keloidosis, and scarring, suggesting a potential avenue for novel treatments.
1 citations
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December 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that Sox9 plays a critical role in maintaining radial glial progenitor cells and regulates the timing of their generation of upper-layer cortical neurons.
1 citations
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January 2003 in “The Pediatric Infectious Disease Journal” This case report describes a 13-year-old boy with febrile illness and hair loss who was diagnosed with an unspecified condition after worsening symptoms on Hospital Day 10, following initial recovery.
November 2024 in “Scientific Reports” In this study, researchers at a tertiary cancer center observed that many male germ cell tumor survivors experienced degrees of hypogonadism and erectile dysfunction, highlighting the clinical need to monitor endocrine health in cancer survivors.
This study found that using SH-SY5Y cell lysate in Western blot analysis may improve the diagnosis of Satoyoshi syndrome by providing more consistent and clear immunoreactive band patterns compared to brain homogenate, potentially leading to earlier diagnosis and treatment.
July 2024 in “ACS Biomaterials Science & Engineering” In this study, researchers used a 3D in vitro organ culture system to show that rifampicin-loaded lipid nanocapsules can penetrate hair follicles more effectively than free rifampicin, highlighting the potential advantage of nanocarrier-based antibiotic treatments for follicular infections.
This study suggests that topically applied thyroid hormones T3 and T4 promote hair growth on human scalp tissues ex vivo, highlighting potential therapeutic use for hair loss conditions like androgenetic alopecia.
This study found that neutrophil-rich hair follicle inflammation caused by a monoclonal antibody targeting murine EGFR in mice involved TNFα and interleukin-1, suggesting these cytokines play a role in EGFR antibody-induced rashes in cancer patients.
This study in mice found that a monoclonal antibody targeting EGFR resulted in skin inflammation mediated by TNFα, suggesting potential pathways for addressing EGFR antibody-induced skin rash in cancer patients.
February 2017 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Hair cortisol measurement is a promising, non-invasive tool for monitoring cortisol exposure over time.
June 2008 in “Experimental Dermatology” This study suggests that combining 17-beta estradiol with prednisolone could accelerate hair regrowth after chemotherapy-induced alopecia in humans, based on preclinical findings using an in vitro model.
December 2005 in “Dermatologic surgery” This study found that while Er:YAG laser therapy can initially improve the appearance of eruptive vellus hair cysts, it was ineffective in preventing early recurrences due to limitations in ablation depth.
This study concluded that the combination of all-trans-retinoic acid and tocopherol-α is not recommended for treating del(5q) myelodysplastic syndromes due to low efficacy and high incidence of adverse effects.
February 1990 in “Pathology, research and practice” This study in rats with a portocaval shunt observed severe ultrastructural damage to the inner ear, associated with zinc deficiency and symptoms resembling liver cirrhosis in humans.
November 2018 in “Journal of Molecular and Cellular Cardiology” This study found that finasteride improved cardiac function and reduced remodeling after myocardial infarction in mice.
26 citations
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June 2016 in “Frontiers in Plant Science” This study describes a method to isolate and analyze young and mature type VI trichomes from wild tomato species using autofluorescence-based cell sorting.
19 citations
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October 2008 in “Journal der Deutschen Dermatologischen Gesellschaft” This article reviews the cutaneous reactions and characteristic skin changes associated with chemotherapy, radiation therapy, and new targeted cancer treatments, reporting no new clinical results.
14 citations
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April 2019 in “PLOS ONE” This study found non-melanoma skin cancer in 7.2% of elderly residents in long-term care facilities in Berlin, highlighting the need for more routine skin cancer screenings in these settings.
6 citations
,
December 2019 in “Frontiers in genetics” In this study, animal model observations suggested that GLI1 expression may reduce cSCC initiation but is not involved in the tumor's aggressiveness.
1 citations
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May 2017 in “Urologe A” This study reports an increase in the use of tamsulosin/finasteride for benign prostatic syndrome in Germany but highlights that reliable comparisons with monotherapies are lacking due to study design deficiencies.
759 citations
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February 2009 in “Current Biology” This review summarizes fundamental concepts and recent advancements in hair follicle biology, including insights from mouse models into broader molecular and cellular processes relevant to regeneration and development.