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The reconstructed skin model from hair follicles functions like human skin in processing chemicals and can be used to test ingredient safety.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Finasteride affects UGT1A4 enzyme, but not enough to cause issues when combined with other drugs.

Topical finasteride at 0.25% is effective and has fewer side effects than oral finasteride for hair loss.

EtG in hair can help detect alcohol use but may be inaccurate in people with certain health conditions.

Food intake, not genetics, affects how the body processes tadalafil and finasteride.

More research is needed to understand how testosterone is maintained in adult males.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Human enzymes can detoxify harmful substances but might also increase their cancer risk.

11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

The traditional herbal formulas Yongdamsagan-Tang and Paljung-san, along with the drug finasteride, can reduce inflammation and may work together without affecting each other's effectiveness against benign prostatic hyperplasia.

Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.

Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

Glutathione helps Arabidopsis roots adapt to low phosphate by regulating a specific growth pathway.

Finasteride breakdown products found in bile and urine, helps understand drug safety and effectiveness.

Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.

New compounds may help treat prostate cancer by reducing cell growth.

Computational methods can speed up and improve the development and safety of herbal drugs.

Genetic mutations can affect female sexual development, requiring personalized medical care.

A new method accurately measures nine specific hormones in human blood.

Finasteride may lower cholesterol and slow heart disease progression.

Researchers found potential urine markers for polycystic ovary syndrome, including testosterone-glucuronide and 11α-hydroxyprogesterone, which may help diagnose the condition.

Father's finasteride use may affect son's fertility and testicular function.

Finasteride helps hair growth and prostate issues but may cause sexual side effects and increase tumor risk.