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Some common medications can harm male fertility, but many effects can be reversed.

New treatments for male hypogonadism are effective and should be personalized.

Cells in hair follicles help create fat cells in the skin by releasing a protein called Sonic Hedgehog.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

Maintaining DNA health in stem cells is key to preventing aging and tissue breakdown.

The nude gene causes skin cell overgrowth and improper development, leading to hair and urinary issues.

Sox2-positive dermal papilla cells have unique characteristics and contribute more to skin and hair follicle formation than Sox2-negative cells.

Korean Red Ginseng has beneficial components that help with stress, immunity, fatigue, memory, blood flow, and disease protection.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

Certain bacteria and fungi are linked to healthy scalps and dandruff, suggesting that the scalp's microbial balance affects its health.

Kennedy's disease leads to muscle weakness and sensory issues, has no cure but manageable symptoms, and future treatments look promising.

Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.

Anti-acne medications may work by reducing the activity of a protein involved in acne development.

Compartmentalized organization might be crucial for stem cells to effectively respond to growth or injury.

Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.

RTA 408 cream protects mice from radiation skin damage.

Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.

A position effect on the TRPS1 gene causes excessive hair growth in humans and mice.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

ZDHHC13 is important for normal liver function and metabolism, affecting mitochondrial activity.

EdnrB signaling helps melanocyte stem cells regenerate and could be targeted to treat pigmentation issues.

Oxidative stress damages hair and contributes to aging, and managing it can help maintain hair health.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.

Skin stem cells maintain and repair the outer layer of skin, with some types being essential for healing wounds.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

Two-photon microscopy helps observe hair follicle stem cell behaviors in mice.

Mutations in the LSS gene cause a rare type of hereditary hair loss.

Edible seeds from the Cucurbitaceae family like pumpkin and watermelon seeds are nutritious and may have health benefits, but eating too much can cause side effects.