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    Research 211–240 of 457

    1. Metabolic Regulation of Hematopoietic Stem Cells in the Hypoxic Niche Cell stem cell · 2011 · 695 citations
    2. The JAK/STAT signaling pathway: from bench to clinic Signal Transduction and Targeted Therapy · 2021 · 489 citations
    3. Wnt/β-catenin signalling: function, biological mechanisms, and therapeutic opportunities Signal Transduction and Targeted Therapy · 2022 · 318 citations
    4. Spermidine/spermine-<i>N</i><sup>1</sup>-acetyltransferase: a key metabolic regulator AJP Endocrinology and Metabolism · 2008 · 305 citations
    5. Biological Function of Long Non-coding RNA (LncRNA) Xist Frontiers in Cell and Developmental Biology · 2021 · 247 citations
    6. Epigenetics of Colorectal Cancer Gastroenterology · 2012 · 218 citations
    7. Epidermolysis bullosa simplex: a paradigm for disorders of tissue fragility 2009 · 189 citations
    8. The Role of the Mammalian Target of Rapamycin (mTOR) in Pulmonary Fibrosis International Journal of Molecular Sciences · 2018 · 177 citations
    9. Biotin and biotinidase deficiency Expert Review of Endocrinology & Metabolism · 2008 · 166 citations
    10. The IL-23/IL-17 Pathway in Inflammatory Skin Diseases: From Bench to Bedside Frontiers in immunology · 2020 · 144 citations
    11. WNT Signaling in Disease Cells · 2019 · 144 citations
    12. Local circadian clock gates cell cycle progression of transient amplifying cells during regenerative hair cycling Proceedings of the National Academy of Sciences of the United States of America · 2013 · 116 citations
    13. Identification of a link between Wnt/β-catenin signalling and the cell fusion pathway Nature Communications · 2011 · 101 citations
    14. Clinical and Immunological Phenotype of Patients With Primary Immunodeficiency Due to Damaging Mutations in NFKB2 Frontiers in immunology · 2019 · 98 citations
    15. The Many Faces of Calcineurin Inhibitor Toxicity—What the FK? Advances in chronic kidney disease · 2020 · 97 citations
    16. NEDD4 and NEDD4L regulate Wnt signalling and intestinal stem cell priming by degrading LGR5 receptor The EMBO Journal · 2019 · 91 citations
    17. White Lupin Cluster Root Acclimation to Phosphorus Deficiency and Root Hair Development Involve Unique Glycerophosphodiester Phosphodiesterases Plant physiology · 2011 · 80 citations
    18. Aberrant Activation of the Hedgehog Signaling Pathway in Malignant Hematological Neoplasms ˜The œAmerican journal of pathology · 2011 · 68 citations
    19. The keratin 19 promoter is potent for cell-specific targeting of genes in transgenic mice Gastroenterology · 2001 · 66 citations
    20. Toll-Like Receptor Function in Acute Wounds Advances in wound care · 2017 · 65 citations
    21. The Skin and Inflamm-Aging Biology · 2023 · 60 citations
    22. Drug repurposing: A novel strategy to target cancer stem cells and therapeutic resistance Genes & Diseases · 2023 · 56 citations
    23. Signature selection analysis reveals candidate genes associated with production traits in Iranian sheep breeds BMC Veterinary Research · 2021 · 55 citations
    24. Role of Endolysosomes in Severe Acute Respiratory Syndrome Coronavirus-2 Infection and Coronavirus Disease 2019 Pathogenesis: Implications for Potential Treatments Frontiers in Pharmacology · 2020 · 55 citations
    25. TGFβ and cancer metastasis: an inflammation link Cancer and Metastasis Reviews · 2010 · 55 citations
    26. Myricetin: A Significant Emphasis on Its Anticancer Potential via the Modulation of Inflammation and Signal Transduction Pathways International Journal of Molecular Sciences · 2023 · 54 citations
    27. Targeting integrin pathways: mechanisms and advances in therapy Signal Transduction and Targeted Therapy · 2023 · 54 citations
    28. SARS-CoV-2 Non-Structural Proteins and Their Roles in Host Immune Evasion Viruses · 2022 · 52 citations
    29. Hydroxyl radical mediates cisplatin-induced apoptosis in human hair follicle dermal papilla cells and keratinocytes through Bcl-2-dependent mechanism APOPTOSIS · 2011 · 52 citations
    30. Ornithine Decarboxylase Expression Leads to Translocation and Activation of Protein Kinase CK2 in Vivo Journal of Biological Chemistry · 1997 · 52 citations