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Targeted therapies for lung cancer are effective but require careful management of side effects to benefit patients.

2011 dermatological research found new skin aging markers, hair loss causes, skin defense mechanisms, and potential for new treatments.

Ripretinib is effective and safe for treating advanced GIST in Chinese patients, particularly for non-gastric GISTs.

A man got six skin cancers within a year after a cell transplant for leukemia but was cancer-free 32 months later; skin checks are important post-transplant.

Janus Kinase inhibitors are effective and have an acceptable safety profile for treating moderate to severe Ulcerative Colitis.

Skin symptoms can indicate endocrine disorders and have various treatments.

Some chemicals can permanently or temporarily remove color from skin and hair, which can be distressing and is not well-regulated in cosmetics.

VEGF helps hair grow and determines follicle size by increasing blood vessel growth.

Hair and nail cells share similar proteins, indicating a common differentiation pathway.

BAY 43-9006 helps control kidney cancer growth but doesn't significantly increase overall survival.

JAK inhibitors are effective in treating various immune-related diseases, not just rheumatoid arthritis.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Hair color production in mice is closely linked to the hair growth phase and may also influence hair growth itself.

Targeted cancer therapies often cause serious skin problems that need careful management.

EGFR inhibitors often cause skin problems and other side effects, but these are usually reversible and can be managed to keep patients comfortable.

Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

JAK inhibitors help with skin conditions but need more research on dosing and safety.

Hair color production is closely linked to the active growth phase of hair in mice and may also influence hair growth itself.

Nerves and chemicals in the body can affect hair growth and loss.

The document concludes that understanding sulfation biology is crucial for creating treatments due to its importance in biological functions and disease.

Hair color loss can indicate the effectiveness of a drug targeting the KIT protein in mice and humans.

Hair keratin-associated proteins are essential for strong hair, with over 80 genes showing specific patterns and variations among people.

Brain-Derived Neurotrophic Factor (BDNF) slows down hair growth and promotes hair follicle regression.

Hair growth is controlled by specific gene clusters and proteins, and cysteine affects hair gene expression in sheep.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Hair follicles in people with alopecia have lower levels of a key blood vessel growth protein.

Targeted cancer therapies have a significant but lower risk of causing hair loss compared to chemotherapy.

Gefitinib can cause skin problems, diarrhea, and nausea, but rarely causes severe lung disease or hair loss.

The gene KAP22-1 affects wool yield and fiber shape in sheep.