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Both ruxolitinib and tofacitinib are effective and safe for treating severe alopecia areata, but relapses are common.

A new protein was made to detect specific skin cell growth receptors and worked in normal skin but not in skin cancer cells.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

Drugs targeting the JAK/STAT pathway can improve atopic dermatitis but vary in effectiveness for vitiligo and alopecia areata, with generally mild safety concerns.

5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.

Stretching skin increases a certain protein that attracts stem cells, helping skin regeneration.

Distinct β-catenin patterns are linked to cell growth, not cell death, in lung cancer.

Beard and scalp hair cells have different gene expressions, which may affect beard growth characteristics.

The TCL1 transgenic mouse model is useful for understanding human B-cell leukemia and testing new treatments.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

PDGF signaling is crucial for maintaining and renewing hair follicle stem cells, which could help treat hair loss.

New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

ALA-PDT is effective and safe for chronic X-ray dermatitis, providing complete or partial remission.

TAF4 is important for skin cell growth and helps prevent skin cancer in mice.

Quercitrin may help treat hair loss by promoting hair growth and improving cell health.

Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.

The document concludes that understanding how adult stem and progenitor cells move is crucial for tissue repair and developing cell therapies.

Consider benefits and risks of new alopecia treatments for safety.

Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.

Green tea may help with skin health and protect against UV damage, but more research is needed to confirm its safety and effectiveness.

Anti-cancer treatments can cause reversible hair loss, skin sensitivity, pigmentation changes, nail damage, and skin reactions, with a need for more research on managing these side effects.

Scientists created tiny particles loaded with a hair growth drug, minoxidil, that specifically target hair follicles and skin cells to potentially improve hair growth.

Sorafenib after liver surgery may increase survival for some liver cancer patients.

Teriflunomide is an effective and safe first-line oral treatment for relapsing multiple sclerosis.

Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.

Leflunomide and anthralin may effectively treat severe alopecia areata.