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MPA increases cancer spread by boosting Eph A2 activity.

Dr. Mario Lacouture recommends preventive and specific treatments for skin side effects caused by EGFR inhibitors to improve patients' quality of life.

Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.

Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.

Planarian regeneration begins with a specific gene activation caused by injury, essential for healing and tissue regrowth.

Using CDK inhibitors on rats showed a reduction in chemotherapy-caused hair loss, but later experiments could not repeat these results.

Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

The article concludes that while we understand a lot about how melanocytes age and how this can prevent cancer, there are still unanswered questions about certain pathways and genes involved.

A certain smell receptor in hair follicles can affect hair growth when activated by a synthetic sandalwood scent.

Both vitiligo and alopecia areata involve an immune response triggered by stress and specific genes, with treatments targeting this pathway showing potential.

The protein folliculin, involved in a rare disease, works with another protein to control how cells stick together and their organization, and changes in this interaction can lead to disease symptoms.

Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.

Baricitinib helps treat several diseases, including COVID-19, but has side effects and needs careful monitoring.

Minoxidil boosts hair growth by triggering growth factor release from specific stem cells.

Blocking JAK/STAT pathways can help treat hair loss from alopecia areata.

Oral JAK inhibitors are effective and safe for treating alopecia areata but may need ongoing use to keep results.

Tofacitinib citrate is effective for moderate-to-severe chronic plaque psoriasis but has safety concerns at higher doses.

Ozone therapy might improve cancer treatment and reduce its side effects.

Lysophosphatidic acid is important for skin health and disease, and could be a target for new skin disorder treatments.

New treatments for advanced skin cancer are improving patient outcomes, but drug resistance and finding the right treatment combinations are still big challenges.

Ruxolitinib may help treat hair loss by reducing inflammation, promoting hair growth signals, and protecting hair follicle immunity.

Troxerutin helps protect skin cells from oxidative stress and may be good for treating hair loss.

DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.

Finasteride boosts stem cell signals for hair growth.

Blue-light activation of TrkA improves hair-follicle stem cells' ability to become neurons and glial cells.

The peptide GPIGS helps hair cells grow and speeds up hair regrowth in mice.

Tofacitinib may be safe for COVID-19 patients with alopecia without worsening symptoms, based on two cases.