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TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Keratins are crucial for cell structure, growth, and disease risk.

Sulforaphane from broccoli can help protect skin from sun damage.

CDP is crucial for lung and hair follicle cell development.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Stem cell niches support, regulate, and coordinate stem cell functions.

Blocking JAK-STAT signaling can lead to hair growth.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Using CDK inhibitors on rats showed a reduction in chemotherapy-caused hair loss, but later experiments could not repeat these results.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

Keratose, derived from human hair, is a non-toxic biomaterial good for tissue regeneration and integrates well with body tissues.

Periodontal ligament stem cells show promise for regrowing tissues but require more research for safe, effective use.

Human dermal fibroblasts are the main cells targeted by a virus that can cause a deadly skin cancer, and a certain inhibitor can effectively block this infection.

Macrophages help heal nerves by aiding the maturation of Schwann cells and are important for nerve repair.

Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.

MIM is crucial for hair follicle formation and regeneration by controlling cilia formation and hedgehog signaling through its interaction with Cortactin and Src.

The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.

The article concludes that the wool follicle is a valuable model for studying tissue interactions and has potential for genetic improvements in wool production.

Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.

Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.

Some drugs can cause skin, nail, and hair problems, which are important for healthcare professionals to recognize and report.

Folliculitis decalvans is a rare scalp condition causing scarring hair loss, treated with long-term antibiotics and other medications, but it often comes back and is hard to manage.

Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.

The document concludes that hair is complex, with a detailed growth cycle, structure, and clinical importance, affecting various scientific and medical fields.

PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.

Olive oil compounds may help prevent cancer in animals, but human results are mixed.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.