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Keratin-associated proteins have ancient origins and were used for different purposes before being adapted for hair in mammals.

Alopecia areata is an autoimmune condition causing hair loss, linked to genetic factors and immune system issues, with no cure yet.

Certain long non-coding RNAs in cashmere goats affect hair growth when treated with a specific growth factor.

TLR3 signaling enhances the immunosuppressive properties of human periodontal ligament stem cells.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Macrophages help heal nerves by aiding the maturation of Schwann cells and are important for nerve repair.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

A protein called CBP is found in prostate cancer and can increase the effectiveness of certain prostate cancer treatments.

Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

Apple extract called procyanidin B-2 was found to greatly increase hair growth.

CIP/KIP proteins help stop cell division and support hair growth.

Ruxolitinib may help treat hair loss by reducing inflammation, promoting hair growth signals, and protecting hair follicle immunity.

The African spiny mouse heals skin without scarring due to different protein activity compared to the common house mouse, which heals with scarring.

Chemotherapy causes complex changes in hair follicle cells that can lead to hair loss.

Temporary ROS production in cultured human hair follicles promotes growth and stem cell activation.

Androgens reduce BMP2, which weakens the ability of certain cells to help hair stem cells become different types of cells.

Biotin helps regulate proteins in the blood, which may explain its role in hair growth.

Acupuncture may improve reproductive and metabolic functions in PCOS without negative side effects, but more research is needed to confirm its effectiveness.

Exosomes from stem cells help hair regrowth by activating a specific signaling pathway.

Rat hair-follicle stem cells can become heart cells with specific supplements.

Effective PCOS treatments require targeting specific signaling pathways.

Plant roots respond to fungus smells by possibly using certain proteins and a plant hormone to change root growth, but more research is needed.

Young women in West Bengal, India, with PCOS often have estrogen resistance, leptin receptor issues, folate deficiency, T2DM, and acanthosis, commonly linked to obesity.

Researchers created a mouse with the same mutation as humans with trichothiodystrophy, showing similar symptoms and confirming the condition is due to defects in DNA repair and gene activity.

The peach gene CTG134 helps control the interaction between auxin and ethylene, which could lead to new agricultural chemicals.

Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.