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Finasteride treatment changes brain steroid levels and receptors, affecting brain function even after stopping treatment.

Baldness in men with prostate cancer is linked to higher levels of certain sex hormones, but chest hair density is not.

Rice bran extract might help prevent hair loss.

Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

5α reductase type 2 enzyme mutation and oxidative stress may increase androgenetic alopecia risk in Egyptians.

Changing the C-ring structure in certain compounds can make them better at blocking a specific human enzyme.

FCE 28260 is a stronger and longer-lasting inhibitor of 5α-reductase than finasteride, which may make it a better treatment for certain medical conditions.

New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.

Some newly made compounds can block an enzyme linked to hair loss and prostate growth, with one in particular being very selective.

Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

Finasteride may cause lasting sexual, mental, and physical symptoms; use with caution.

Finasteride and dutasteride are effective in treating male hair loss but can cause sexual side effects and birth defects.

Ganoderma lucidum, a type of mushroom, may help treat enlarged prostate by blocking testosterone conversion.

Finasteride effectively reduces hair loss by decreasing androgen levels.

Dutasteride injections can help hair growth in androgenic alopecia but need more research for long-term use.

Medicines for enlarged prostate may raise the risk of breast growth and tenderness but not breast cancer.

Seablite root extract may help prevent hair loss and promote hair growth.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

Dihydrotestosterone and 5α-Reductase play a role in hair loss and prostate health, and finasteride can increase hair growth in men without affecting sperm production, but it doesn't work for postmenopausal women with hair loss.

Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.

Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.

Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.

PNU157706 reduced rat sperm movement and fertility without affecting offspring health.

Testosterone increases muscle mass regardless of DHT conversion blocking.

The triterpenoids from Ganoderma lucidum can block testosterone effects and may help treat enlarged prostate.

Both drugs lower DHT levels, with GI198745 being more effective.

Finasteride exposure harms tadpole reproduction and hormone balance.

The document concludes that various cosmetic and drug treatments are available for hirsutism, and some new drugs show promise.