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PDE inhibitors, especially PDE4 inhibitors like apremilast, are effective for certain inflammatory skin conditions but have side effects and can be costly.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

Terbinafine is the most effective medicine for fungal nail infections, especially for diabetics and those with weak immune systems.

Germacrone from Curcuma aeruginosa may help treat conditions related to male hormones by blocking a specific enzyme.

New genes linked to ichthyosis were found, but there's still no cure; treatment options are improving.

The research explains how a human enzyme binds and processes its substrate, which could relate to its role in biological functions and hair loss.

Human hair follicles can make and process prostaglandins, which may affect hair growth.

Hair follicle studies suggest that maintaining telomere length could help treat hair loss and graying, but it's uncertain if mouse results apply to humans.

Low oxygen areas help maintain and protect blood stem cells by using a simple sugar breakdown process for energy and managing their activity levels.

Combined arsenic and low oxygen stress alters root growth to help plants absorb nutrients.

Targeting ornithine decarboxylase can help prevent skin cancer.

Inhibiting ornithine decarboxylase may help prevent certain skin cancers.

Melatonin, a hormone, can help protect skin from aging by reducing stress, inflammation, and damage, and may also help treat hair loss in women.

Sulfotransferase SULT1A1 activity may predict minoxidil treatment success for hair loss.

Melatonin, usually known for sleep regulation, also has antioxidant properties that can protect skin, stimulate hair growth, and improve skin conditions, with topical application being more effective than oral use.

5α-reductase inhibitors, like finasteride and dutasteride, effectively treat BPH, male baldness, and hirsutism, with potential for acne and prostate cancer prevention.

Finasteride may improve prostate cancer treatment outcomes.

A new anti-baldness patch effectively treats hair loss by blocking enzymes linked to the condition.

Human skin's melanocytes respond to light by changing shape, producing pigments and hormones, which may affect sleep patterns.

Topical finasteride doesn't reduce DHT levels, hinting at an endocrine role in hair loss.

Melatonin stimulates the skin components of ram's scrotum during their non-breeding season.

Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.

Hair color production is closely linked to the active growth phase of hair in mice and may also influence hair growth itself.

Hair color production in mice is closely linked to the hair growth phase and may also influence hair growth itself.

Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

Hormone therapy may increase migraines in transgender women and decrease them in transgender men; more research is needed on migraine management in transgender individuals.

Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

Androgenetic alopecia is more common in Indian men than women, and family history is a strong risk factor.