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Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

A49T gene variant linked to higher prostate cancer risk, lower hormone levels, and slightly reduced balding risk.

Finasteride's polymorphic form affects capsule quality and drug effect, requiring strict control.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

Alopecia areata is a type of hair loss that can lead to complete baldness, often associated with other autoimmune conditions, and half of the cases may see hair return within a year.

Four patients with a type of rickets and hair loss had different mutations in their vitamin D receptor gene, causing it to not work properly.

Cholesterol-related compounds can stop hair growth and cause inflammation in a type of scarring hair loss.

The document discusses various eye conditions and their treatments, including a rare eye cancer in a baby, vision loss from a cancer drug, cataracts from a baldness treatment, a rare skin disorder, and a specific type of eye disease diagnosed with a special imaging technique.

New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.

PRP combined with minoxidil is the most effective and safe treatment for male pattern baldness.

Most adrenal cortex tumors are benign and non-secreting, but proper diagnosis and treatment are important due to the rare possibility of cancer.

Type 3 Innate Lymphoid Cells help maintain skin health and balance, and are involved in skin diseases and healing.

The document concludes that Syndromes of Severe Insulin Resistance are rare disorders with limited treatment options.

Honokiol might help reduce male skin aging by maintaining testosterone levels.

Plant extracts like Avicennia marina, Boehmeria nipononivea, and Camellia sinensis could potentially treat hair loss with fewer side effects than synthetic drugs.

Mexican women's hair is between Asian and Caucasian hair in thickness and shape, with varied strength and some damage.

The research reveals how early embryonic mouse skin develops from simple to complex structures, identifying various cell types and their roles in this process.

Managing metabolic syndrome needs both lifestyle changes and medical treatments.

Boys with less severe EDA mutations in XLHED have milder symptoms and better sweat and hair production.

Severe insulin resistance can be managed with medication, lifestyle changes, and treatment for related conditions.

Model improves accuracy in predicting hair loss effects.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

Memantine may slightly improve memory in people with Down syndrome, but more research is needed.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Thai rice bran extracts, especially from Tubtim Chumphae rice, can significantly reduce the activity of hair loss genes, with x-tocopherol showing potential as an anti-hair loss product.

Genetic factors affect hair loss, and molecular testing may help predict, diagnose, and treat it.

Taking Propecia might lead to the development of cataracts.

Different drugs can treat high male hormone levels in women, but they have various effects and some may harm a fetus.

The document concludes that careful diagnosis is crucial for chromosome 13q deletion syndrome, tamoxifen can cause reversible eye damage, finasteride may be linked to cataracts, and OCT is useful for diagnosing macular diseases.

Topical minoxidil is effective and safe for hair regrowth in Middle Eastern men with early baldness, with better results in younger patients and certain types of baldness.