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    Research 31–60 of 1000+

    1. Natural Product-Inspired Bis(trifluoromethyl) Phenyl Hydroxycinnamate Derivatives as Promising Nonsteroidal Inhibitors of Human Steroid 5α-Reductase Type-1: Synthesis, <i>In Vitro</i>, and <i>In Silico</i> Studies ACS Omega · 2025
    2. Natural Product-InspiredBis(trifluoromethyl) PhenylHydroxycinnamate Derivatives as Promising Nonsteroidal Inhibitorsof Human Steroid 5α-Reductase Type-1: Synthesis, <i>InVitro</i>, and <i>In Silico</i> Studies OPAL (Open@LaTrobe) (La Trobe University) · 2025
    3. 1424 METHYLATION AND DECREASED EXPRESSION OF 5-ALPHA REDUCTASE 2 IN HUMAN PROSATE SAMPLES: IMPLICATIONS FOR RESISTANCE TO THERAPY FOR BPH The Journal of Urology · 2010
    4. Design, synthesis and biological evaluation of novel androst-3,5-diene-3-carboxylic acid derivatives as inhibitors of 5α-reductase type 1 and 2 Steroids · 2017 · 8 citations
    5. A role for steroid 5 alpha-reductase 1 in vascular remodeling during endometrial decidualization Frontiers in endocrinology · 2022 · 4 citations
    6. Change in hair growth-related gene expression profile in human isolated hair follicles induced by 5-alpha reductase inhibitors – dutasteride and finasteride – in the presence of testosterone Singapore Medical Journal · 2021 · 1 citations
    7. Genetic analysis of 5 α reductase type 2 enzyme in relation to oxidative stress in cases of androgenetic alopecia in a sample of egyptian population Our Dermatology Online · 2013 · 1 citations
    8. Absence of Interaction Between 5α‐Reductase Inhibitors and Glucocorticoids on Incidence of Myocardial Infarction in People With Type 2 Diabetes Diabetes Obesity and Metabolism · 2026
    9. A Role for Steroid 5 alpha-reductase 1 in Vascular Remodelling During Endometrial Decidualisation bioRxiv (Cold Spring Harbor Laboratory) · 2022
    10. Exercise activates the PI3K-AKT signal pathway by decreasing the expression of 5α-reductase type 1 in PCOS rats Scientific reports · 2018 · 28 citations
    11. Exploring the Inhibitory Potential of Phytosterols β-Sitosterol, Stigmasterol, and Campesterol on 5-Alpha Reductase Activity in the Human Prostate: An In Vitro and In Silico Approach Plants · 2024 · 12 citations
    12. Synthesis and biological evaluation of esters of 16-formyl-17-methoxy-dehydroepiandrosterone derivatives as inhibitors of 5α-reductase type 2 Journal of Enzyme Inhibition and Medicinal Chemistry · 2015 · 5 citations
    13. Extract of <i>Plumbago zeylanica</i> enhances the growth of hair follicle dermal papilla cells with down‐regulation of 5α‐reductase type II Journal of Cosmetic Dermatology · 2020 · 4 citations
    14. Determination of the potency of a novel saw palmetto supercritical CO2 extract (SPSE) for 5&alpha;-reductase isoform II inhibition using a cell-free in vitro test system Research and reports in urology · 2016 · 3 citations
    15. In silico screening of effective inhibitor of 5α-reductase type 1 for androgenic alopecia treatment Natural Product Research · 2021 · 1 citations
    16. FRI-02 FROM GIRLS TO BOYS TO OLDER MEN, THE INTERESTING TALE OF THE GUEVEDOCES AND 5-ALPHA REDUCTASE INHIBITORS The Journal of Urology · 2016
    17. Topical MK-386 (M), an inhibitor of 5α-reductase (5αr) type I, suppresses sebum dht. Clinical Pharmacology & Therapeutics · 1996
    18. High-performance liquid chromatographic determination of the enantiomers of the benzoquinolinone LY 191704, a human type 1 5α-reductase inhibitor, in plasma Journal of Chromatography B: Biomedical Sciences and Applications · 1997 · 1 citations
    19. Determination of the potency of a novel saw palmetto supercritical CO2 extract (SPSE) for 5α-reductase isoform II inhibition using a cell-free in vitro test system DOAJ (DOAJ: Directory of Open Access Journals) · 2016 · 2 citations
    20. Immunolocalization of 5α-Reductase Isozymes in Acne Lesions and Normal Skin Archives of dermatology · 2000 · 45 citations
    21. Effect of Sparasis crispa Extract on 5α-Reductase Gene in Dermal Papilla Cells Asia-Pacific journal of convergent research interchange · 2021
    22. Synthesis and 5α-reductase inhibitory activity of 8-substituted benzo[ƒ]quinolinones derived from palladium mediated coupling reactions Bioorganic & Medicinal Chemistry Letters · 1998 · 14 citations
    23. Novel prospectives of shikimic acid and Prunus mume extract for enhancing bioactivity on 5α-reductase and stability in cosmetic patches for acne treatment Frontiers in Natural Products · 2026
    24. Bifunctional sodium hyaluronate microneedle patches integrating 5α-reductase and ROS regulation for boosted hair regeneration International Journal of Biological Macromolecules · 2025
    25. Investigation of Antioxidant Activity of Cynanchi Wilfordii Radix and Inhibitory Effect of 5α-reductase mRNA in Human Dermal Papilla Cells Dong-ui saengni byeongni hakoeji · 2017
    26. The 5α-Recluctase System and Its Inhibitors Dermatology · 1996 · 124 citations
    27. Synthesis of phenanthridin-3-one derivatives: Non-steroidal inhibitors of steroid 5-α-reductase Tetrahedron Letters · 1995 · 20 citations
    28. Novel 5α-Reductase Inhibitors:  Synthesis, Structure−Activity Studies, and Pharmacokinetic Profile of Phenoxybenzoylphenyl Acetic Acids Journal of Medicinal Chemistry · 2005 · 18 citations
    29. Evaluating the safety profile of α-1 blockers, 5α-reductase inhibitors, and PDE5I for BPH: a disproportionality analysis of real-world adverse events based on FDA adverse event reporting system (FAERS) Figshare · 2026
    30. Evaluating the safety profile of α-1 blockers, 5α-reductase inhibitors, and PDE5I for BPH: a disproportionality analysis of real-world adverse events based on FDA adverse event reporting system (FAERS) Figshare · 2026