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    Research 61–90 of 1000+

    1. Predominant expression of 5 alpha-reductase type 1 in pubic skin from normal subjects and hirsute patients. 1996 · 11 citations
    2. Discovery and Clinical Development of Dutasteride, a Potent Dual 5α- Reductase Inhibitor Current topics in medicinal chemistry · 2006 · 58 citations
    3. Torilin from<i>Torilis japonica,</i>as a New Inhibitor of Testosterone 5α-Reductase Planta Medica · 2003 · 22 citations
    4. Avicequinone C Isolated from Avicennia marina Exhibits 5α-Reductase-Type 1 Inhibitory Activity Using an Androgenic Alopecia Relevant Cell-Based Assay System Molecules · 2014 · 19 citations
    5. Effect of C-ring modifications in benzo[c]quinolizin-3-ones, new selective inhibitors of human 5α-reductase 1 Bioorganic & Medicinal Chemistry · 2001 · 12 citations
    6. 5α‐Reductase inhibitors and prostatic disease Clinical endocrinology · 1994 · 21 citations
    7. Immunolocalization of 5α-Reductase Isozymes in Acne Lesions and Normal Skin Archives of dermatology · 2000 · 45 citations
    8. 5α‐Reductase Inhibitors Andrology · 1997 · 17 citations
    9. Dihydrotestosterone and the Concept of 5&alpha;&ndash;Reductase Inhibition in Human Benign Prostatic Hyperplasia European Urology · 2000 · 184 citations
    10. SÍNDROME PÓS-FINASTERIDA E O IMPACTO DOS INIBIDORES DA 5-ALFA REDUTASE NOS EIXOS NEUROENDÓCRINO E METABÓLICO RECIMA21 - Revista Científica Multidisciplinar - ISSN 2675-6218 · 2026
    11. Pharmacokinetic parameters and mechanisms of inhibition of rat type 1 and 2 steroid 5α-reductases: determinants for different in vivo activities of GI198745 and finasteride in the rat 3 3Abbreviations: r5AR1, rat 5α-reductase 1; r5AR2, rat 5α-reductase 2; and DHT, dihydrotestosterone. Biochemical Pharmacology · 2001 · 22 citations
    12. The 5 Alpha-Reductase Isozyme Family: A Review of Basic Biology and Their Role in Human Diseases Advances in Urology · 2011 · 218 citations
    13. Benzo[<i>c</i>]quinolizin-3-ones: A Novel Class of Potent and Selective Nonsteroidal Inhibitors of Human Steroid 5α-Reductase 1 Journal of Medicinal Chemistry · 2000 · 28 citations
    14. 1424 METHYLATION AND DECREASED EXPRESSION OF 5-ALPHA REDUCTASE 2 IN HUMAN PROSATE SAMPLES: IMPLICATIONS FOR RESISTANCE TO THERAPY FOR BPH The Journal of Urology · 2010
    15. The Role of 5αR Inhibitors in the Early Growth of Pca Cells Urologia Journal · 2005
    16. 5-alpha-reductase inhibitors are associated with reduced frequency of COVID-19 symptoms in males with androgenetic alopecia (vol 35, pg e243, 2021) Journal of The European Academy of Dermatology and Venereology · 2021
    17. Human type 3 5α-reductase is expressed in peripheral tissues at higher levels than types 1 and 2 and its activity is potently inhibited by finasteride and dutasteride Hormone Molecular Biology and Clinical Investigation · 2010 · 45 citations
    18. Synthesis, Biological Evaluation and Molecular Docking of Avicequinone C Analogues as Potential Steroid 5α-Reductase Inhibitors Chemical & Pharmaceutical Bulletin · 2017 · 13 citations
    19. Synthesis and Biological Evaluation of 4-(4-(Alkyl-and Phenylaminocarbonyl)benzoyl)benzoic Acid Derivatives as Non-steroidal Inhibitors of Steroid 5α-Reductase Isozymes 1 and 2 Archiv Der Pharmazie · 2002 · 8 citations
    20. Pharmacogenetic analysis of human steroid 5α reductase type II: comparison of finasteride and dutasteride Journal of Molecular Endocrinology · 2005 · 26 citations
    21. Change in Hair Growth-related Gene Expression Profile in Human Isolated Hair Follicles Induced by 5-alpha Reductase Inhibitors, Dutasteride and Finasteride, in the Presence of Testosterone 2019
    22. Mechanism-Based Inhibition of Human Steroid 5α-Reductase by Finasteride: Enzyme-Catalyzed Formation of NADP−Dihydrofinasteride, a Potent Bisubstrate Analog Inhibitor Journal of the American Chemical Society · 1996 · 136 citations
    23. Dihydrotestosteron und die Rolle der 5α-Reduktasehemmer bei der benignen Prostatahyperplasie Der Urologe · 2002 · 24 citations
    24. 5α-reductase activity in the prostate Urology · 2001 · 237 citations
    25. Finasteride reduces serum PSA to a similar extent at 1 mg and 5 mg daily doses Nature Clinical Practice Urology · 2007
    26. Sexual Dysfunction Related to Drugs: a Critical Review. Part V: α-Blocker and 5-ARI Drugs Pharmacopsychiatry · 2015 · 15 citations
    27. 3,3-Diphenylpentane skeleton as a steroid skeleton substitute: Novel inhibitors of human 5α-reductase 1 Bioorganic & medicinal chemistry letters · 2007 · 13 citations
    28. 5-Alpha-Reductase Inhibitors Reduce Remission Time of COVID-19: Results From a Randomized Double Blind Placebo Controlled Interventional Trial in 130 SARS-CoV-2 Positive Men medRxiv (Cold Spring Harbor Laboratory) · 2020 · 5 citations
    29. Hair Are the Rankings—5-α Reductase Inhibitors and Minoxidil in Male Androgenetic Alopecia JAMA Dermatology · 2022 · 1 citations
    30. The Long-Term Effect Of Specific Type II 5α-Reductase Inhibition With Finasteride on Bone Mineral Density in Men: Results of a 4-Year Placebo Controlled Trial The Journal of Urology · 2002 · 11 citations