2 citations,
January 2010 in “Hormone Molecular Biology and Clinical Investigation” Low dose finasteride decreases certain steroids, possibly increasing depression risk.
Dermal stem cells help regenerate hair follicles and heal skin wounds.
19 citations,
May 2012 in “The journal of investigative dermatology/Journal of investigative dermatology” The type 3 IP3 receptor is important for controlling hair loss and growth.
January 2019 in “Przegląd Dermatologiczny” An 87-year-old woman was diagnosed with type 3 autoimmune polyendocrine syndrome and had multiple autoimmune issues.
5 citations,
January 2021 in “iScience” Using a combination of specific cell cycle regulators is better for safely keeping hair root cells alive indefinitely compared to cancer-related methods.
12 citations,
June 2001 in “Bioorganic & Medicinal Chemistry” Changing the C-ring structure in certain compounds can make them better at blocking a specific human enzyme.
12 citations,
April 1995 in “Journal of Medicinal Chemistry” The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.
January 2000 in “Expert Opinion on Therapeutic Patents” The document highlights various patents for new compounds with potential treatments for multiple diseases, including cancer, hormonal disorders, and diabetes.
6 citations,
February 2019 in “Scientific reports” A brain-produced steroid causes increased scratching in mice with a skin condition similar to eczema.
7 citations,
August 2013 in “Journal of the European Academy of Dermatology and Venereology” Less than a quarter of alopecia areata cases were unusual forms or had paradoxical regrowth.
Integrin alphavbeta6 is important for wound healing and hair growth, and blocking it may improve these processes.
44 citations,
July 2012 in “Endocrine Practice” We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.
42 citations,
December 2011 in “The journal of immunology/The Journal of immunology” RANKL causes lymph nodes to grow by making certain cells multiply.
March 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” A specific immune response helps control mite populations on the skin, maintaining healthy hair follicles.
21 citations,
April 2018 in “Journal of Dermatological Science” Cilostazol helps hair grow by making hair root cells grow faster and changing growth factor levels.
260 citations,
July 2010 in “Cell” Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.
December 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Stress can cause a type of hair loss in mice lacking the CCHCR1 gene.
11 citations,
July 2008 in “Facial Plastic Surgery Clinics of North America” Hair restoration surgery redistributes existing hair to achieve a natural look, with visible regrowth in 3-4 months and rare complications, mostly aesthetic.
15 citations,
February 2014 in “BMC Research Notes” The X5 Hairlaser might help treat male hair loss, but more research is needed.
3 citations,
February 2022 in “Frontiers in cell and developmental biology” A specific RNA molecule, circCOL1A1, affects the growth and quality of goat hair by interacting with miR-149-5p and influencing cell growth pathways.
July 2018 in “Journal of Evolution of medical and Dental Sciences” Men with common hair loss (AGA) are more likely to have metabolic syndrome, which increases heart disease risk. Early screening could help prevent heart disease. More research is needed to understand this relationship better.
25 citations,
September 2018 in “Molecular Biology of the Cell” Blocking Wnt/β-catenin signaling with EGF receptor is necessary for proper hair growth.
6 citations,
August 2009 in “Mini-reviews in Medicinal Chemistry” Different drugs can treat high male hormone levels in women, but they have various effects and some may harm a fetus.
40 citations,
May 2010 in “Australasian Journal of Dermatology” Chronic hair shedding may be caused by less variation in hair growth times and might stop on its own after several years.
17 citations,
March 2020 in “Frontiers in Chemistry” Compounds from the plant Mammea siamensis may help treat hair loss.
15 citations,
February 2017 in “Nursing Clinics of North America” Targeted cancer therapies can cause skin side effects, which should be treated early to help patients' quality of life and treatment adherence.
9 citations,
November 2019 in “Cell calcium” The STIM1 R304W mutation in mice leads to bone changes and teeth hair growth.
2 citations,
December 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” miR-29 is a key factor that accelerates aging.
1 citations,
May 2018 in “Journal of Evolution of medical and Dental Sciences” Platelet Rich Plasma (PRP) injections can effectively reduce hair loss and improve hair growth in both men and women suffering from androgenic alopecia.
December 2023 in “Annals of phytomedicine” Dutasteride is more effective than finasteride for hair loss treatment.