Search

everythinglearnresearchcommunity

for

Search:↓

Men with early balding showed higher levels of certain genes linked to hair loss and possibly prostate cancer.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

5α-reductase inhibitors like finasteride and dutasteride can help treat skin disorders stimulated by androgens, such as hair loss and acne.

GI198745 is more potent and longer-lasting than finasteride, potentially better for treating hair loss.

Finasteride effectively treats male hair loss, improving growth and density.

Men taking dutasteride or finasteride have a slightly higher risk of developing type 2 diabetes.

No consistent link between genotype and phenotype in 5-α-Reductase type 2 deficiency.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

Finasteride, when given in high oral doses to pregnant monkeys, caused genital abnormalities in male fetuses, but not in female fetuses or those exposed to intravenous finasteride.

Minoxidil may help treat hair loss by reducing the activity of a specific enzyme linked to baldness.

LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.

The enzyme type 1 5α-reductase is more active in the hair follicle's lower part than in the skin's outer layer.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

New compounds were made that effectively block enzymes related to prostate issues and hair loss.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

New chemicals were made that can block an enzyme linked to hair loss, prostate growth, and acne.

Finasteride, a drug used for certain conditions, can cause serious side effects like sexual dysfunction, suicidal thoughts, and increased diabetes risk, and there's a need for more awareness and research about these effects.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.

Finasteride-treated male rats' offspring had altered glucose metabolism, potentially increasing diabetes risk.

Herbal extracts may help hair grow and could be an alternative to synthetic hair loss treatments.

Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.

Plant extracts like Avicennia marina, Boehmeria nipononivea, and Camellia sinensis could potentially treat hair loss with fewer side effects than synthetic drugs.

11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.

Managing metabolic syndrome needs both lifestyle changes and medical treatments.

Thujae occidentalis semen extract may help treat male pattern baldness by blocking a hair loss-related enzyme and reducing hair loss in mice.

Thai rice bran extracts, especially from Tubtim Chumphae rice, can significantly reduce the activity of hair loss genes, with x-tocopherol showing potential as an anti-hair loss product.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.