research Cytostatics and Immunosuppressive Drugs: Toxicities and Management
Some cancer and immune system drugs can cause serious side effects, including heart, lung, nerve, and organ damage, which need careful monitoring and management.
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research Effect of 5α-Dihydrotestosterone and Testosterone on Apoptosis in Human Dermal Papilla Cells
High levels of testosterone and 5α-DHT can lead to cell death in cells important for hair growth.
research Cyclosporin A-Induced Hair Growth in Mice Is Associated with Inhibition of Calcineurin-Dependent Activation of NFAT in Follicular Keratinocytes
Cyclosporin A helps mice grow hair by blocking a specific protein activity in skin cells.
research Several Selective Protein Kinase C Inhibitors Including Procyanidins Promote Hair Growth
Certain substances that block a specific protein help promote hair growth.
research In Vitro Main Pathways of Steroid Action in Cultured Hair Follicle Cells: Vascular Approach
Steroids, particularly estrogens and 5α-reductase inhibitors, affect blood vessel-related hair growth processes in hair follicle cells.
research A Role for Steroid 5 Alpha-Reductase 1 in Vascular Remodeling During Endometrial Decidualization
The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.
research Activation of Transient Receptor Potential Vanilloid-3 Inhibits Human Hair Growth
Activating TRPV3 stops human hair growth.
research Aldesleukin
Aldesleukin can treat certain cancers and increase HIV patient CD4+ counts but often causes severe side effects.
research Update on Frontal Fibrosing Alopecia
Best treatment for Frontal Fibrosing Alopecia is 5-alpha-reductase inhibitors and intralesional corticosteroids.
research Androgenetic Alopecia and Microinflammation
Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.
research Biphenotypic Leukemia
Acute leukemias with the Philadelphia chromosome may be biphenotypic, and identifying this is important for proper treatment.
research Advances in Nucleoside Monophosphate Prodrugs as Anti-HCV Agents
New treatments for Hepatitis C show promise but need more research to confirm their safety and effectiveness for clinical use.
research Inhibition of Rat 5α-Reductase Activity and Testosterone-Induced Sebum Synthesis in Hamster Sebocytes by an Extract of Quercus Acutissima Cortex
An extract from Quercus acutissima bark was found to reduce sebum production and block an enzyme linked to acne.
research Drug Safety Evaluation of Exemestane
Exemestane is effective and safe for treating certain breast cancers, with mild side effects, but needs more research on long-term effects.
research Adverse Cutaneous Effects of Psychotropic Medications
Psychotropic medications can cause skin problems, including serious conditions, and patients should be monitored closely.
research Issues in the Treatment of Epilepsy
Treating epilepsy is complex, requiring careful drug choice and patient adherence to manage seizures and side effects.
research Cardiodermatology in the Physician’s Practice
Skin problems like psoriasis and systemic sclerosis can increase the risk of heart disease, so doctors should watch for heart risks in patients with these conditions.
research Use of Oral Contraceptives in the Management of Acne
Birth control pills with low-dose estrogen and antiandrogenic progestins can effectively treat acne.
research Anal Involvement in Pemphigus Vulgaris: Study on Recurrence and Treatment Outcomes
Most patients with anal Pemphigus Vulgaris had repeated episodes but fully recovered with treatment, without long-term problems.
research Polymorphisms in Genes Involved in Steroidogenesis in the Development of Severe Acne
Certain gene variations are linked to a higher risk of severe acne, suggesting a genetic influence on the condition.
research Clinical Manifestations of Toxic Shock Syndrome
Toxic Shock Syndrome mainly affects menstruating women, can recur, and is linked to staph bacteria, with rapid treatment being crucial.
research 5α-Reductase Activity in the Human Hair Follicle Concentrates in the Dermal Papilla
The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.
research Crystal Structure of 3-Oxo-4-Aza-5-Alpha-Androstone-17 β-Tert-Butyl Carboxamide with an O···H–(C, N) Acceptor Four-Center Hydrogen Bond
The research shows that hydrogen bonds greatly affect the crystal structure of a Finasteride derivative.
research The Relationship Between ABO And Rh Blood Groups With Alopecia Areata
AB+ blood group is more common in alopecia areata patients.
research Optimization and Transfollicular Delivery of Finasteride-Loaded Proniosomes for Hair Growth Stimulation in C57BL/6Mlac Mice
Finasteride-loaded proniosomes effectively promote hair growth in mice.
research Current Understanding and Treatment of Sex Hormone-Related Hair Diseases
Sex hormones affect hair growth and loss, and treatments for related hair diseases include various medications, hair transplantation, and light therapy.
research Alcohol and Prostate Cancer: Time to Draw Conclusions
Drinking a lot of alcohol increases the risk of prostate cancer and can worsen the condition.
research Update on Hormonal Therapy in Hidradenitis Suppurativa
Hormonal therapies, especially antiandrogens, can help manage Hidradenitis Suppurativa.
research Dual Effects of 5α-Reductase Inhibitor Dutasteride on Androgenetic Alopecia and Acne Vulgaris
Dutasteride improved both hair loss and acne in two young men.
research Whole-Cell Bioprocessing of Human Fetal Cells for Tissue Engineering of Skin
Fetal cells could improve skin repair with minimal scarring and are a potential ready-to-use solution for tissue engineering.