research Tether-Induced Tenosynovitis: The Importance of an Intact Skin Barrier
An intact skin barrier is crucial to prevent infection in cases of tether-induced tenosynovitis.
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research The Use of Diphencyprone in Dermatology: A Retrospective Audit
Diphencyprone treatment protocols could be simplified as no harm occurred despite not fully following them.
research Oral Cyclosporin Does Not Arrest Progression of Androgenetic Alopecia
Cyclosporin doesn't stop hair loss.
research The Rationale for Inhibiting 5α-Reductase Isoenzymes in the Prevention and Treatment of Prostate Cancer
Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.
research Finasteride Treatment of Patterned Hair Loss in Normoandrogenic Postmenopausal Women
Finasteride can slow hair loss and promote growth in postmenopausal women.
research Body Composition Changes and Inhibition of Fat Development In Vivo Implicate Androgen in Regulation of Stem Cell Lineage Allocation
Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.
research The Potential Role of Minoxidil in the Hair Transplantation Setting
Minoxidil helps stabilize hair loss, increase density, and reduce shedding after hair transplant surgery.
research Chemical Mechanism of the Covalent Modification of 5-Alpha-Reductases by Finasteride as Probed by Secondary Tritium Isotope Effects
Finasteride modifies 5-alpha-reductases through a two-step process, affecting inhibitor potency and possibly causing side effects.
research Naevus Trichilemmocysticus: The First Pediatric Case of a Newly Delineated Organoid Naevus
The first pediatric case of naevus trichilemmocysticus was documented.
research Endocrinology and Metabolism News, August 2005: Effects of Finasteride on Benign Prostatic Hyperplasia Tissues
Finasteride causes temporary cell death in BPH tissues.
research Combinatorial Expression of Cell Cycle Regulators Is More Suitable for Immortalization Than Oncogenic Methods in Dermal Papilla Cells
Using a combination of specific cell cycle regulators is better for safely keeping hair root cells alive indefinitely compared to cancer-related methods.
research Abstracts from the Current Global Literature: Finasteride and Sexual Dysfunction
Finasteride, a hair loss drug, can cause sexual side effects like erectile dysfunction in 2.1%-3.8% of users, but these usually go away with time or if the drug is stopped. Despite this, its impact on sexual function is minimal for most men.
research The Immune Functions of Keratinocytes in Skin Wound Healing
Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.
research Cepharanthine: A Review of the Antiviral Potential of a Japanese-Approved Alopecia Drug in COVID-19
Cepharanthine, a Japanese hair loss drug, shows promise as a COVID-19 treatment but needs more testing.
research Are Sex Discordant Outcomes in COVID-19 Related to Sex Hormones?
Sex hormones may affect COVID-19 severity, with men often faring worse, and targeting related pathways could offer treatment options.
research The Frequency of Metabolic Syndrome Is Higher Among Brazilian Women With PCOS, Menstrual Irregularity, and Hyperandrogenism
Brazilian women with PCOS and both menstrual irregularity and high male hormone levels have a higher chance of having metabolic syndrome.
research 5-Alpha Reductase Inhibitors in Androgenetic Alopecia: Shifting Paradigms, Current Concepts, Comparative Efficacy, and Safety
Dutasteride works better than finasteride for hair loss, with both being safe to use.
research 17β-Estradiol Enhances Vascular Endothelial Growth Factor Production and Dihydrotestosterone Antagonizes the Enhancement via the Regulation of Adenylate Cyclase in Differentiated THP-1 Cells
Estrogen increases blood vessel growth factor production, while testosterone blocks this increase.
research Nonsurgical Therapy for Hair Loss
Some nonsurgical hair loss treatments are effective, especially if started early.
research Epidemiology, Management, and the Associated Burden of Mental Health Illness, Atopic and Autoimmune Conditions, and Common Infections in Alopecia Areata: Protocol for an Observational Study Series
People with alopecia areata have higher rates of mental health issues, autoimmune diseases, and infections.
research Whole Exome Sequencing in Alopecia Areata Identifies Rare Variants in KRT82
Rare changes in the KRT82 gene are linked to a higher risk of Alopecia Areata.
research Frequency and Associated Factors of Hair Loss Among Patients With Inflammatory Bowel Disease
Hair loss is common in IBD patients, and some medications may lower the risk.
research The Effect of 1540-nm Fractional Erbium-Glass Laser in the Treatment of Androgenic Alopecia
Laser treatment effectively increases hair density and thickness in androgenic alopecia.
research Effect of Citrullus Colocynthis Schrad on Testosterone-Induced Benign Prostatic Hyperplasia
Citrullus colocynthis fruit extract and its compound may help treat enlarged prostate.
research Gender Difference in the Relationship Between Ferritin and Homeostasis Model Assessment of Insulin Resistance in Non-Diabetic Korean Adults
Iron levels are linked to insulin resistance in men and postmenopausal women, but not in premenopausal women.
research Topical Products for Human Hair Regeneration: A Comparative Study on an Animal Model
Minoxidil was the most effective treatment for hair regrowth in rats compared to Aminexil or Kerium.
research Transcriptome Analysis Reveals the Genetic Basis Underlying the Development of Skin Appendages and Immunity in Hedgehog (Atelerix Albiventris)
Genes related to keratin, skin cell differentiation, and immune functions are key in hedgehog skin and spine development.
research Rapid Characterization of the Functional and Pharmacological Consequences of Cantú Syndrome KATP Channel Mutations in Intact Cells
Kir6.1 mutations in Cantú syndrome increase channel sensitivity and hyperpolarization, while SUR2B mutations do not.
research Prevalence of Polycystic Ovarian Syndrome (PCOS) Like Symptoms in the General Practice of an Obstetrics and Gynecological Office on the Island of Tobago: A Retrospective Chart Analysis
19.7% of Afro-Caribbean women in Tobago have PCOS.
research Integrated-Omics Profiling Unveils the Disparities of Host Defense to ECM Scaffolds During Wound Healing in Aged Individuals
Aged individuals heal wounds less effectively due to specific immune cell issues.