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The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

Some natural remedies may help with hair regrowth, but more research is needed to confirm their effectiveness and safety.

Resistance exercise can reduce muscle protein issues caused by finasteride.

Finasteride effectively improves hair growth and slows hair loss in men with male pattern baldness.

Minoxidil is the only FDA-approved topical drug for treating male or female pattern hair loss, and other medications like finasteride and dutasteride can also increase hair growth.

Testosterone is crucial for development, growth, and various body functions in mammals.

Post-finasteride syndrome's existence is uncertain; more research needed.

Antiandrogens are the main treatment for hirsutism, with individualized care and safe, affordable options needed.

Some extracts from woods and fungi can promote hair growth better than a known hair growth substance.

Finasteride can treat hair loss, but may have side effects; evaluate and inform patients of risks.

New compounds may help treat prostate cancer by reducing cell growth.

A49T gene variant linked to higher prostate cancer risk, lower hormone levels, and slightly reduced balding risk.

Dihydrotestosterone treatment can help penis growth in boys with 5α-reductase deficiency but doesn't fully normalize size after puberty.

Testosterone and dihydrotestosterone treatments can help with penile growth in males with 5α-reductase type 2 deficiency, with dihydrotestosterone being more effective in infancy.

The enzyme type 1 5α-reductase is more active in the hair follicle's lower part than in the skin's outer layer.

LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

New steroidal compounds moderately block an enzyme related to testosterone conversion, less effectively than finasteride.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Thujae occidentalis semen extract may help treat male pattern baldness by blocking a hair loss-related enzyme and reducing hair loss in mice.

Sebocytes play a key role in controlling androgen levels in human skin.

Testosterone helps human pancreatic cells increase insulin release.

People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.

Hair characteristics might be early signs of Type 2 Diabetes and could help with early prevention.

Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.

5α-reductase inhibitors, like finasteride and dutasteride, effectively treat BPH, male baldness, and hirsutism, with potential for acne and prostate cancer prevention.

Researchers developed a new method to find substances in herbs that can block a specific enzyme linked to hair loss.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

5-alpha reductase deficiency leads to male sexual development issues and treatments like finasteride help with prostate enlargement and hair loss.

Four-amino acid part makes enzyme sensitive to finasteride.