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5α reductase type 2 enzyme mutation and oxidative stress may increase androgenetic alopecia risk in Egyptians.

Finasteride may cause kidney damage.

Gene differences may affect baldness treatment response in Korean men.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Thai rice bran extracts, especially from Tubtim Chumphae rice, can significantly reduce the activity of hair loss genes, with x-tocopherol showing potential as an anti-hair loss product.

Thujae occidentalis semen extract may help treat male pattern baldness by blocking a hair loss-related enzyme and reducing hair loss in mice.

Phyllanthus niruri extract may help treat hair loss by promoting hair growth and blocking a hair loss-related enzyme.

Dutasteride is more effective than finasteride for hair loss treatment.

Avicequinone C, a compound found in the Avicennia marina plant, can reduce hair loss by inhibiting a hormone linked to androgenic alopecia.

Finasteride's effect on hair loss and prostate enlargement depends on its binding to an enzyme, with maximum impact at 0.2 mg dose.

Scientists made new substances that can block an enzyme linked to prostate issues and hair loss, with potential for creating a new treatment.

New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Certain drugs that block specific enzymes can help treat prostate diseases.

New compounds may help treat prostate cancer by reducing cell growth.

5α reductase inhibitors treat hair loss but may cause sexual side effects and risks.

Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Finasteride negatively affects fish reproduction and gonadal development.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Finasteride affects urinary steroid profiles and can potentially hide steroid abuse in sports drug testing.

Finasteride exposure harms tadpole reproduction and hormone balance.

Finasteride inhibits enzyme activity in rhesus macaques, suggesting they're useful for evaluating similar drugs.

A certain mutation in the fetal alpha 5-reductase gene is linked to a higher risk of late miscarriage.

Some Thai plants, especially Carthamus tinctorius, could help prevent hair loss and promote hair growth without adverse effects.

Finasteride and dutasteride effectively treat hair loss in men and women, but may cause side effects like low libido and depression.

Muscles can make their own androgens, which may help muscle growth.

New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.

The document concludes that accurate measurement of serum androgens is crucial for diagnosing hyperandrogenism.