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Women with acne may have a higher chance of having PCOS, which can lead to other health problems.

PCOS causes menstrual issues, infertility, and long-term health risks.

Polycystic Ovary Syndrome (PCOS) is a complex disorder with both immediate and long-term health effects, including menstrual issues, infertility, and increased risk of diabetes and heart disease.

Finasteride lowers PSA levels about the same whether taken at 1 mg or 5 mg daily.

Finasteride reduces prostate cancer risk but may increase high-grade tumors; new drugs and better diagnosis are in development, but funding and industry commitment are challenges.

Early signs of PCOS in girls, like irregular periods and polycystic ovaries, suggest a need for early diagnosis and intervention to prevent further health issues.

Finasteride, a drug used for certain conditions, can cause serious side effects like sexual dysfunction, suicidal thoughts, and increased diabetes risk, and there's a need for more awareness and research about these effects.

5AR inhibitors like finasteride and dutasteride improve hair growth and slow hair loss in male pattern baldness.

Recent genetic insights show that low-renin hypertension includes a range from essential hypertension to secondary or familial forms, affecting diagnosis and treatment.

Herbal extracts may help hair grow and could be an alternative to synthetic hair loss treatments.

Frontal fibrosing alopecia mostly affects postmenopausal women, with diagnosis often delayed by 3 years.

People with early onset baldness (AGA) have higher blood sugar levels and lower sex hormone-binding globulin (SHBG) levels, suggesting SHBG could predict high blood sugar in these individuals.

Insufficient androgen action in male fetuses can cause genital development issues due to genetic mutations or environmental chemicals.

Male children's genital development issues can be caused by genetic mutations or environmental factors affecting hormone action.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Understanding how DHT works is important for diagnosing and treating hormone-related disorders.

Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.

Natural killer cells play a key role in autoimmune skin diseases like pemphigus vulgaris.

Androgens may influence bladder cancer progression by affecting cellular behavior.

Changing the C-ring structure in certain compounds can make them better at blocking a specific human enzyme.

Finasteride treatment in male rats can reduce fertility and affect sperm development in their offspring.

Honokiol might help reduce male skin aging by maintaining testosterone levels.

Baricitinib and its combination with lonafarnib improve fat cell formation in certain genetic disorders.

Male yak hair growth is influenced by DHT synthesis, which is promoted by 5α-red1 and AR during growth phases, while E2 may inhibit growth through ERα.

5α-reductase inhibitors like finasteride and dutasteride can help treat skin disorders stimulated by androgens, such as hair loss and acne.

Finasteride helps manage male hair loss, but realistic expectations and support are crucial.

Molecular diagnostics help identify genetic defects causing endocrine diseases, improving diagnosis and treatment options.

Plant extracts like Avicennia marina, Boehmeria nipononivea, and Camellia sinensis could potentially treat hair loss with fewer side effects than synthetic drugs.

The plant extract and minoxidil both reduce hair loss by lowering specific gene expressions.

Hair loss in Androgenetic Alopecia is caused by genetics, aging, and lifestyle, leading to hair follicle shrinkage and related health risks.